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Temocapril hydrochloride

🥰Excellent
Catalog No. T6698Cas No. 110221-44-8
Alias Temocapril HCl, CS-622 HCl

Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.

Temocapril hydrochloride

Temocapril hydrochloride

🥰Excellent
Purity: 99.26%
Catalog No. T6698Alias Temocapril HCl, CS-622 HClCas No. 110221-44-8
Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
Pack SizePriceAvailabilityQuantity
5 mg$31In Stock
10 mg$48In Stock
25 mg$95In Stock
50 mg$148In Stock
100 mg$232In Stock
200 mg$343In Stock
1 mL x 10 mM (in DMSO)$35In Stock
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Purity:99.26%
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Product Introduction

Bioactivity
Description
Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
Kinase Assay
C2C12 cells are seeded into 96-well plates at 2,000 cells per well in DMEM supplemented with 2% FBS. The wells are treated in quadruplicate with BMP ligands and LDN-193189 or vehicle. The cells are collected after 6 d in culture in 50 μL Tris-buffered saline and 1% Triton X-100. The lysates are added to p-nitro-phenylphosphate reagent in 96-well plates for 1 h and then evaluated alkaline phosphatase activity (absorbance at 405 nm). Cell viability are measured and quantity by Cell Titer Aqueous One (absorbance at 490 nm), using replicate wells treated identically to those used for alkaline phosphatase measurements[1].
AliasTemocapril HCl, CS-622 HCl
Chemical Properties
Molecular Weight513.07
FormulaC23H28N2O5S2·HCl
Cas No.110221-44-8
SmilesCCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CS[C@@H](CN(C1=O)CC(=O)O)c1cccs1.Cl
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 95 mg/mL (185.2 mM)
DMSO: 95 mg/mL (185.2 mM)
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM1.9491 mL9.7453 mL19.4905 mL97.4526 mL
5 mM0.3898 mL1.9491 mL3.8981 mL19.4905 mL
10 mM0.1949 mL0.9745 mL1.9491 mL9.7453 mL
20 mM0.0975 mL0.4873 mL0.9745 mL4.8726 mL
50 mM0.0390 mL0.1949 mL0.3898 mL1.9491 mL
100 mM0.0195 mL0.0975 mL0.1949 mL0.9745 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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