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Tin-protoporphyrin IX dichloride
🥰Excellent
Catalog No. T13161Cas No. 14325-05-4
Alias SnPPIX dichloride, SnPPIX
Tin-protoporphyrin IX dichloride (SnPPIX dichloride) is an HO-1) inhibitor with antiviral activity that inhibits dengue and yellow fever viruses.
Tin-protoporphyrin IX dichloride
🥰Excellent
Purity: 98%
Catalog No. T13161Alias SnPPIX dichloride, SnPPIXCas No. 14325-05-4
Tin-protoporphyrin IX dichloride (SnPPIX dichloride) is an HO-1) inhibitor with antiviral activity that inhibits dengue and yellow fever viruses.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $45 | In Stock | |
| 5 mg | $106 | In Stock | |
| 10 mg | $172 | In Stock | |
| 25 mg | $288 | In Stock | |
| 50 mg | $432 | In Stock |
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Purity:98%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Tin-protoporphyrin IX dichloride (SnPPIX dichloride) is an HO-1) inhibitor with antiviral activity that inhibits dengue and yellow fever viruses. |
| Targets&IC50 | HO-1: |
| In vitro | In Capan-1, CD18/HPAF, and PDAC cells, Tin protoporphyrin IX dichloride (20 μM, 50 μM; 24 or 72 hours) inhibited proliferation of Capan-1 and CD18/HPAF cells and inhibited growth of PDAC cells at 50 μM[1]. |
| In vivo | In male and female athymic nude mice with PDAC cell-derived xenograft tumors, Tin protoporphyrin IX dichloride (5 mg/kg; Intraperitoneal injection; on days 1, 4, 6, 8, 11, 13, 15, 18, and 20) inhibited tumor growth and sensitized tumors to chemotherapy (Gemcitabine)[1]. |
| Alias | SnPPIX dichloride, SnPPIX |
| Molecular Weight | 750.26 |
| Formula | C34H32Cl2N4O4Sn |
| Cas No. | 14325-05-4 |
| Smiles | O=C(CCC1=C(C)C2=CC3=C(C)C(C=C)=C4C=C5C(C)=C(C=C)C6=[N]5[Sn+4]([Cl-])([Cl-])([N-]43)([N-]78)[N]2=C1C=C8C(CCC([O-])=O)=C(C)C7=C6)[O-].[H+].[H+] |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | 0.1M NaOH: 10 mg/mL (13.3 mM), Sonication is recommended.  DMSO: 5 mg/mL (6.6 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO/0.1M NaOH
0.1M NaOH
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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