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Vonafexor

🥰Excellent
Catalog No. T8471Cas No. 1192171-69-9
Alias pxl007, PLX007, EYP001

Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects

Vonafexor

Vonafexor

🥰Excellent
Purity: 98.74%
Catalog No. T8471Alias pxl007, PLX007, EYP001Cas No. 1192171-69-9
Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects
Pack SizePriceAvailabilityQuantity
2 mg33 â‚¬In Stock
5 mg51 â‚¬In Stock
10 mg84 â‚¬In Stock
25 mg175 â‚¬In Stock
100 mg471 â‚¬In Stock
1 mL x 10 mM (in DMSO)56 â‚¬In Stock
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Purity:98.74%
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Product Introduction

Bioactivity
Description
Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects
Aliaspxl007, PLX007, EYP001
Chemical Properties
Molecular Weight489.76
FormulaC19H15Cl3N2O5S
Cas No.1192171-69-9
SmilesOC(=O)c1cc2c(Cl)c(ccc2o1)N1CCN(CC1)S(=O)(=O)c1c(Cl)cccc1Cl
Relative Density.1.604 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 22.5 mg/mL (45.94 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0418 mL10.2091 mL20.4182 mL102.0908 mL
5 mM0.4084 mL2.0418 mL4.0836 mL20.4182 mL
10 mM0.2042 mL1.0209 mL2.0418 mL10.2091 mL
20 mM0.1021 mL0.5105 mL1.0209 mL5.1045 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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