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Werner syndrome RecQ helicase-IN-1 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $55 | In Stock | |
5 mg | $127 | In Stock | |
10 mg | $186 | In Stock | |
25 mg | $312 | In Stock | |
50 mg | $528 | In Stock | |
100 mg | $846 | In Stock | |
500 mg | $1,890 | In Stock | |
1 mL x 10 mM (in DMSO) | $865 | In Stock |
Description | Werner syndrome RecQ helicase-IN-1 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer. |
Targets&IC50 | WRN ATPase:100 nM |
In vitro | Werner syndrome RecQ helicase-IN-1 exhibits an IC50 value of 100 nM for WRN ATPase, and demonstrates GI50 values of 50 nM and >10 μM for SW48 and DLD1 WRN-KO cell lines, respectively.[1] |
Molecular Weight | 702.08 |
Formula | C31H31ClF3N9O5 |
Cas No. | 2869954-34-5 |
Smiles | C(C(NC1=C(Cl)C=C(C(F)(F)F)C=C1)=O)N2C=3N(C(=O)C(=C2CC)N4CCN(C(=O)C=5C(O)=C(C)N=CN5)CC4)N=C(N3)C=6CCOCC6 |
Storage | store at low temperature,keep away from direct sunlight,keep away from moisture | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 99.7 mg/mL (142.01 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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