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YLF-466D
🥰Excellent
Catalog No. T13368Cas No. 1273323-67-3
Alias C24
YLF-466D (C24) is a novel AMPK activator that inhibits platelet aggregation.
YLF-466D
🥰Excellent
Purity: 98.04%
Catalog No. T13368Alias C24Cas No. 1273323-67-3
YLF-466D (C24) is a novel AMPK activator that inhibits platelet aggregation.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $31 | In Stock | |
| 5 mg | $76 | In Stock | |
| 10 mg | $119 | In Stock | |
| 25 mg | $209 | In Stock | |
| 50 mg | $298 | In Stock | |
| 100 mg | $413 | In Stock | |
| 200 mg | $568 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $79 | In Stock |
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CitedSelect Batch
Purity:98.04%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | YLF-466D (C24) is a novel AMPK activator that inhibits platelet aggregation. |
| In vitro | The study investigates the impact of YLF-466D on platelet AMPK activation and its potential to inhibit platelet aggregation. Activation of platelet AMPK by YLF-466D is confirmed through phosphorylation at Thr172, leading to the suppression of platelet aggregation triggered by thrombin, ADP, and collagen. This demonstrates that YLF-466D's anti-aggregatory effect is broad and not specific to the type of platelet agonist. The effects of YLF-466D on AMPK activation and aggregation inhibition are concentration-dependent, showing maximal effectiveness at 150 μM. The IC50 values for inhibiting aggregation induced by thrombin, ADP, and collagen are approximately 84, 55, and 87 μM, respectively. |
| Alias | C24 |
| Molecular Weight | 465.93 |
| Formula | C29H20ClNO3 |
| Cas No. | 1273323-67-3 |
| Smiles | OC(=O)c1cccc(CN2C(=O)\C(=C(/c3ccccc3)c3ccc(Cl)cc3)c3ccccc23)c1 |
| Relative Density. | 1.358 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90 mg/mL (193.2 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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