Shopping Cart
- Remove All
Your shopping cart is currently empty
YM90K
🥰Excellent
Catalog No. T8435Cas No. 154164-30-4
Alias YM 90K
YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.
YM90K
🥰Excellent
Purity: 100%
Catalog No. T8435Alias YM 90KCas No. 154164-30-4
YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $80 | In Stock | |
| 5 mg | $178 | In Stock | |
| 10 mg | $272 | In Stock | |
| 25 mg | $448 | In Stock | |
| 50 mg | $630 | In Stock | |
| 100 mg | $852 | In Stock | |
| 200 mg | $1,130 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "YM90K"
L-Glutamic acid
glutamic acid, glutacid, (S)-Glutamic acid, (+)-L-Glutamic acid
T2A249756-86-0
L-Glutamic acid (Glutaminol) acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
- $42
Size
QTY
L-Glutamine
Cited
L-Glutamic acid 5-amide
T0326L56-85-9
L-Glutamine (L-Glutamic acid 5-amide), a non-essential amino acid, is synthesized from glutamic acid and ammonia.
- $29
Size
QTY
CitedL-Glutamic acid monosodium salt
MSG, Monosodium glutamate, Glutavene, Glutacyl, Ajinomoto
T6871142-47-2
L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
- $33
Size
QTY
glycine Cited
Glycosthene, Glycolixir, Glycocoll, Aminoacetic acid, 2-Aminoacetic acid
T2O272856-40-6
glycine (2-Aminoacetic acid) is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
- $41
Size
QTY
CitedO-Phospho-L-serine
Phosphoserine, L-SOP, L-Serine O-phosphate, Dexfosfoserine
T1324407-41-0
O-Phospho-L-serine (Phosphoserine) is the phosphoric acid ester of serine.
- $33
Size
QTY
Evans blue
Direct Blue 53, C.I. 23860
T0313314-13-6
Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).
- $41
Size
QTY
Mephenesin
Mephedan, Memphenesin, Decontractyl, Cresoxydiol
T001559-47-2
Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.
- $33
Size
QTY
Linalool
Phantol, Linalol, (±)-Linalool
T2S226478-70-6
1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury through induction of antioxidant defense via Nrf2 activating and reduction inflammatory response via NF-κB inhibition. 3. Linalool biosynthesis and accumulation might be involved in plant defense against bacterial and fungal pathogens and be associated with field resistance to citrus canker. 4. Linalool significantly increased the expression of antioxidant enzymes regulated by Nrf-2 and diminished lung tissue levels of several pro-inflammatory cytokines, including tumor necrosis factor α (TNF-α) and interleukin (IL)-6.
- $29
Size
QTY
Direct Blue 1
Pontamine sky blue, Chicago Sky Blue 6B
T21942610-05-1
Direct Blue 1 (Pontamine sky blue), a counterstain for background autofluorescence in immunofluorescence histochemistry, structurally resembles glutamate and operates as a potent, competitive VGLUT inhibitor, not impacting plasma membrane transporters. This compound stands out as the inaugural small molecule PrP ligand to inhibit Aβ binding.
- $42
Size
QTY
D-Cycloserine
RO-1-9213
T158968-41-7
D-Cycloserine (RO-1-9213) is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents.
- $43
Size
QTY
Piracetam
UCB-6215
T04267491-74-9
Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
- $45
Size
QTY
Decanoic Acid
Decoic acid, Caprynic acid, CAPRIC ACID
T3379334-48-5
Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.
- $42
Size
QTY
Select Batch
Purity:100%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor. |
| Targets&IC50 | AMPA receptor:84 nM (Ki), Kainate receptor:2.2 μM (Ki), NMDAR:37 μM (Ki) |
| In vivo | In a global ischemia model, YM90K (15 mg/kg i.p. x 3), NBQX (30 mg/kg i.p. x 3) and CNQX (60 mg/kg i.p. x 3) significantly prevented the delayed neuronal death in the hippocampal CA1 region in Mongolian gerbils when administered 1 h after 5-min ischemia.?In addition, the therapeutic time window for the neuroprotective effect of YM90K (30 mg/kg i.p. x 3) was 6 h. In a focal ischemia model, YM90K (30 mg/kg i.v. bolus+10 mg/kg/h for 4 h) reduced the volume of ischemic damage in the cerebral cortex in F344 rats[1]. |
| Alias | YM 90K |
| Molecular Weight | 309.66 |
| Formula | C11H8ClN5O4 |
| Cas No. | 154164-30-4 |
| Smiles | Cl.[O-][N+](=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1-n1ccnc1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO: Slightly soluble  |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy YM90K | purchase YM90K | YM90K cost | order YM90K | YM90K chemical structure | YM90K in vivo | YM90K formula | YM90K molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.