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(+)-Medioresinol

Catalog No. TN1919   CAS 40957-99-1
Synonyms: Medioresinol

(+)-Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity via reduction in the amount of α2-secretase, it is a potentially valuable antiamyloidogenic agent for the prevention and treatment of Alzheimer disease. (+)-Medioresinol has anti-bacterial, antifungal and anti-biofilm activities.

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(+)-Medioresinol Chemical Structure
(+)-Medioresinol, CAS 40957-99-1
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Biological Description
Chemical Properties
Storage & Solubility Information
Description (+)-Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity via reduction in the amount of α2-secretase, it is a potentially valuable antiamyloidogenic agent for the prevention and treatment of Alzheimer disease. (+)-Medioresinol has anti-bacterial, antifungal and anti-biofilm activities.
In vitro Antibacterial effects of (+)-Medioresinol isolated from stem bark of Sambucus williamsii and its synergistic activities in combination with antibiotics such as ampicillin, cefotaxime, and chloramphenicol were tested by antibacterial susceptibility testing and checkerboard assay. (+)-Medioresinol possessed antibacterial effects against antibiotics-susceptible- or antibiotics-resistant strains. Most of combinations between (+)-Medioresinol and each antibiotic showed synergistic interaction (fractional inhibitory concentration index ?≤ 0.5) against bacterial strains including antibiotics-resistant Pseudomonas aeruginosa. Furthermore, the antibiofilm effect of (+)-Medioresinol alone or in combination with each antibiotic was investigated[1]
Synonyms Medioresinol
Molecular Weight 388.41
Formula C21H24O7
CAS No. 40957-99-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Synergistic antibacterial and antibiofilm effect between (+)-medioresinol and antibiotics in vitro.Appl Biochem Biotechnol. 2013 Aug;170(8):1934-41.

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Keywords

(+)-Medioresinol 40957-99-1 Immunology/Inflammation Microbiology/Virology Neuroscience Antifection ROS Beta Amyloid (+) Medioresinol Medioresinol (+)Medioresinol inhibitor inhibit

 

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