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(-)-Hydroxycitric acid lactone

Catalog No. T12045Cas No. 27750-13-6
Alias Garcinia lactone

(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a potent inhibitor of ATP citrate lyase, an enzyme that catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA.

(-)-Hydroxycitric acid lactone

(-)-Hydroxycitric acid lactone

Purity: 99.91%
Catalog No. T12045Alias Garcinia lactoneCas No. 27750-13-6
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a potent inhibitor of ATP citrate lyase, an enzyme that catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA.
Pack SizePriceAvailabilityQuantity
1 mg$64In Stock
2 mg$93In Stock
5 mg$155In Stock
10 mg$247In Stock
25 mg$418In Stock
50 mg$596In Stock
1 mL x 10 mM (in DMSO)$123In Stock
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Purity:99.91%
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Product Introduction

Bioactivity
Description
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a potent inhibitor of ATP citrate lyase, an enzyme that catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA.
In vivo
Garcinia lactone fed chicken for a period of 4 weeks significantly decreases body weight at 2000 and 3000 mg/kg[2].
AliasGarcinia lactone
Chemical Properties
Molecular Weight190.11
FormulaC6H6O7
Cas No.27750-13-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/ml (315.61 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.2601 mL26.3006 mL52.6011 mL263.0056 mL
5 mM1.0520 mL5.2601 mL10.5202 mL52.6011 mL
10 mM0.5260 mL2.6301 mL5.2601 mL26.3006 mL
20 mM0.2630 mL1.3150 mL2.6301 mL13.1503 mL
50 mM0.1052 mL0.5260 mL1.0520 mL5.2601 mL
100 mM0.0526 mL0.2630 mL0.5260 mL2.6301 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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