Search Result

Search Results for " intake "

Targets

105

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1898	HS024	HS 024	Melanocortin Receptor
	HS024 is a highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-...		Melanocortin Receptor
T8425	Linoleoyl Ethanolamide		TRP/TRPV Channel
	Linoleoyl Ethanolamide is an endocannabinoid agent. It acts by binding to TRPV1 increasing ERK phosphorylation and AP-1 dependent transcription in CB-receptor in an independent manner.		TRP/TRPV Channel
T6658	SB-408124		OX Receptor
	SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.		OX Receptor
T6140	SB-334867 free base	SB334867A free base,SB-334867,SB 334867,SB334867	OX Receptor
	SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.		OX Receptor
TP1793	Nociceptin (1-13), amide		Opioid Receptor
	Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes.		Opioid Receptor
T26986	Cevoglitazar	LBM-642,LBM 642,LBM642	PPAR
	Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.		PPAR
T76664	Adropin (34-76) (human, mouse, rat)
	Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance independent of obesity or food intake.
T0001	Iron(II) fumarate	Ferrous fumarate,Iron Fumarate	Others
	Iron(II) fumarate (Iron Fumarate) is the iron(II) salt of fumaric acid, a reddish-orange powder, applied to supply iron intake.		Others
T15006	Dirlotapide	CP742033,Slentrol	Others , CETP
	Dirlotapide (CP742033) is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide reduces food intake in a dose-dependent manner, possibly by ...		Others , CETP
TP1305	LEP(116-130)(mouse)		Others
	Leptin (116-130),mouse(C64H109N19O24S),a peptide with the sequence Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2. Leptin is an adipocyte-derived hormone that acts as a major regulator for food intake an...		Others
T15679	L 152804		Neuropeptide Y Receptor
	L 152804 is a specific antagonist of the neuropeptide Y Y5 receptor and modulates food intake and energy expenditure thus causing weight loss in diet-induced obese mice.		Neuropeptide Y Receptor
T11451	GPI-1046		Others , HIV Protease
	GPI-1046 is an immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in PFC and NAc-core.		Others , HIV Protease
TP1996	MCH(human, mouse, rat)	MCH (human, mouse, rat)	GPR , Melanin-concentrating Hormone Receptor (MCHR)
	MCH(human, mouse, rat) is a potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 and 0.1 nM at MCH1 and MCH2 receptors respectively). Increase...		GPR , Melanin-concentrating Hormone Receptor (MCHR)
TP1984L	[D-Trp34]-Neuropeptide Y Acetate	[D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base)	Neuropeptide Y Receptor
	[D-Trp34]-Neuropeptide Y Acetate is a potent and selective agonist of neuropeptide Y (NPY) Y5 receptor. [D-Trp34]-Neuropeptide acetate Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-...		Neuropeptide Y Receptor
TP1889	MCL0020	MCL 0020	Melanocortin Receptor
	MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly reverses stress-induced anorexia but has no e...		Melanocortin Receptor
T4411	DAMGO TFA (78123-71-4(Free base))		Opioid Receptor
	Potent, selective agonist of Mu-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines and chemokine receptors through TGF-beta1. Increases food int...		Opioid Receptor
TP2279L	Obestatin (rat) acetate		GHSR
	Obestatin (rat) acetate is an endogenous ligand of G-protein coupled receptor 39 (GPR39). Obestatin (rat) acetate has anti-inflammatory, anti-myocardial infarction and antioxidant properties. Obestatin (rat) acetate supp...		GHSR
TP2015L	HS 014 acetate(207678-81-7 free base)		Melanocortin Receptor
	HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and no...		Melanocortin Receptor
T8720	PRX-07034 hydrochloride	PRX-07034	5-HT Receptor
	PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a poten...		5-HT Receptor
T62929	RLX-33		ERK , RXFP receptor
	RLX-33 is a potent and selective antagonist of relaxin family peptide 3 (RXFP3) that crosses the blood-brain barrier and also blocks relaxin 3-induced ERK1/2 phosphorylation. RLX-33 can block the increase in food intake ...		ERK , RXFP receptor
TP1992L	M40 acetate(143896-17-7 free base)		Neuropeptide Y Receptor
	M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates ...		Neuropeptide Y Receptor
T26305	U 67827E	N-Ac-Asp-tyr(So3H)-nle-gly-trp-nle-asp-phe-NH2,U-67827E,U67827E
	U 67827E is a long-lasting cholecystokinin agonist. It acts by decreases food intake.
TP2279	Obestatin(rat)	Obestatin (rat)	Others
	Endogenous peptide that suppresses food intake and body weight-gain		Others
T16086	MK-0493		Others
	MK-0493 is an effective and selective agonist of the melanocortin receptor 4 (MC4R). It also demonstrated significant reductions in energy intake.		Others
T31073	CP-671906	CP-671906-01,UNII-GLZ1WA47Q8
	CP-671906 is a neuropeptide Y1 receptor antagonist which increases blood pressure and food intake in rat models.
T68565	ANN33840
	ANN33840 is a novel selective 5-HT2C agonist with >300-fold functional selectivity over 5-HT2B and >70-fold functional selectivity over 5-HT2A, reducing food intake in an acute rat feeding model.
TP1835	Enterostatin(human,mouse,rat)	Enterostatin, human, mouse, rat
	Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.
T35631	Peptide YY (human) (trifluoroacetate salt)	Peptide Tyrosine Tyrosine
	Peptide YY (PYY) is a 36-amino acid peptide and anorectic gut hormone agonist for the neuropeptide Y receptors Y1, Y2, Y5, and Y6 with EC50 values of 0.7, 0.58, 1, and 0.8 nM, respectively, for supression of forskolin-in...
T35793	JMV3002	JMV3002
	Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrel...
T5406	SNAP 94847	SNAP-94847	GPR , Melanin-concentrating Hormone Receptor (MCHR)
	SNAP 94847 (SNAP-94847) is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces food intake in mice.		GPR , Melanin-concentrating Hormone Receptor (MCHR)
T26935	C108297	C-108297,C 108297
	C108297 is a glucocorticoid receptor modulator. C108297 prevents both diet-induced obesity and inflammation. C108297 decreased food and fructose intake and increased lipolysis in white adipose tissue (WAT) and free fatty...
TP1941	Ac-RYYRWK-NH2
	Potent, selective partial agonist peptide for the NOP receptor (Ki = 0.71 nM). Selective over μ, δ and κ opioid receptors (IC50 > 4000 nM). Increases food intake in vivo.
T27550	HMR-1426	HMR 1426,HMR1426
	HMR-1426 is gastric emptying inhibitor. HMR1426 shows an anorectic potential in rats and decreased body weight and fat mass. This was achieved solely by reducing food intake without influencing overall energy expenditure...
T62179	Rel-O-2050
	rel-O-2050 (Compound O-2050) is a neutral cannabinoid CB1receptor antagonist that reduces food intake in mice.
TP1139	Orexin B, human	Human orexin B
	Orexin B, human is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively. Orexin B is a hypothalamatic neuropeptide stimulating food intake in rats.
T71001	GSK-598809
	GSK598809 is a selective D(3)R antagonist recently progressed in Phase I trials. GSK-598809 may decrease the rewarding effects of contextual cues associated with drug intake preclinically, which may reduce drug craving i...
T29938	AM-3102	KDS-5104,AM 3102,Methyl oleoylethanolamide
	AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and red...
T81625	Obestatin(human) TFA
	Obestatin(human) TFA, an endogenous peptide originating from the same prepropeptide as ghrelin, is known to suppress food intake and reduce weight gain in rats.
T38959	BMS-604992 dihydrochloride	EX-1314 dihydrochloride,BMS-604992 dihydrochloride
	BMS-604992 (EX-1314) dihydrochloride is a selective and orally active small-molecule agonist of the growth hormone secretagogue receptor (GHSR). It exhibits high-affinity binding (k i = 2.3 nM) and potent functional acti...
T40876	BMS-604992 free base	BMS-604992 free base,EX-1314 free base
	BMS-604992 (EX-1314) free base is a selective, orally active small-molecule growth hormone secretagogue receptor (GHSR) agonist. It exhibits high-affinity binding (k i = 2.3 nM) and potent functional activity (EC 50 = 0....
T37783	2,5-Anhydro-D-mannitol
	2,5-Anhydro-D-mannitol is an antimetabolic fructose analogue that increases food intake in rats at doses of 50-800 mg/kg by inhibiting gluconeogenesis and glycogenolysis in the liver.. It is phosphorylated in the liver, ...
TP2073	BigLEN(mouse)	BigLEN (mouse)
	GPR171 agonist. ProSAAS-derived neuropeptide. Regulates food intake in mice. Inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynap...
T37131	MS 15203
	Potent and selective GPR171 partial agonist (EC50 = 90 nM; 28% inhibition of forskolin activated adenylyl cyclase activity in rat hypothalamic memebranes). Exhibits minimal binding to a panel of ~70 GPCRs and 10 other re...
TP1963	[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide	cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide,[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide
	Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM)...
T81390	Prolactin-Releasing Peptide (1-31) (rat)
	Prolactin-Releasing Peptide (1-31) (rat) serves as a ligand for the UHR-1/GRP10 receptor, moderating fasting-induced food intake and elevating plasma concentrations of LH, FSH, and testosterone in rats [1] [2].
TP1916	[D-Phe12,Leu14]-Bombesin
	Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro (IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo.
T37371	4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid
	4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid is an unusual polyunsaturated fatty acid (PUFA) generated during the synthesis of docosahexaenoic acid-d5 . While the physiological properties of this compound are not ...
T82733	Cholecystokinin	CCK-33(human),Cholecystokinin-33(human)
	Cholecystokinin, a peptide hormone, functions as a hunger suppressant by inhibiting food intake and promoting the digestion of fat and protein, and is employed in gastrointestinal system research [1] [2] [3].
TP2015	HS014	HS 014
	Potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and nociception in mice fo...
TP1148	Glucagon-like peptide 1 (1-37), human	HuGLP-1
	Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor.Pancreatic hormone synthesized by post-translational processing of proglucagon. Unlike truncated forms of GLP-1, it has no effect on ...

Compounds

HS024

TP1898

Synonym: HS 024

Target: Melanocortin Receptor

Linoleoyl Ethanolamide

T8425

Synonym:

Target: TRP/TRPV Channel

Synonym: SB334867A free base,SB-334867,SB 334867,SB334867

Target: OX Receptor

Nociceptin (1-13), amide

TP1793

Synonym:

Target: Opioid Receptor

Cevoglitazar

T26986

Synonym: LBM-642,LBM 642,LBM642

Target: PPAR

Adropin (34-76) (human, mouse, rat)

Synonym: Ferrous fumarate,Iron Fumarate

Target: Others

Dirlotapide

T15006

Synonym: CP742033,Slentrol

Target: Neuropeptide Y Receptor

GPI-1046

T11451

Synonym:

Target: Others, HIV Protease

MCH(human, mouse, rat)

TP1996

Synonym: MCH (human, mouse, rat)

Target: GPR, Melanin-concentrating Hormone Receptor (MCHR)

[D-Trp34]-Neuropeptide Y Acetate

TP1984L

Synonym: [D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base)

Target: Neuropeptide Y Receptor

MCL0020

TP1889

Synonym: MCL 0020

Target: Melanocortin Receptor

DAMGO TFA (78123-71-4(Free base))

T4411

Synonym:

Target: Opioid Receptor

Obestatin (rat) acetate

TP2279L

Synonym:

Target: GHSR

HS 014 acetate(207678-81-7 free base)

TP2015L

Synonym:

Target: Melanocortin Receptor

PRX-07034 hydrochloride

T8720

Synonym: PRX-07034

Target: 5-HT Receptor

RLX-33

T62929

Synonym:

Target: ERK, RXFP receptor

M40 acetate(143896-17-7 free base)

TP1992L

Synonym:

Target: Neuropeptide Y Receptor

U 67827E

T26305

Synonym: N-Ac-Asp-tyr(So3H)-nle-gly-trp-nle-asp-phe-NH2,U-67827E,U67827E

Target:

Obestatin(rat)

TP2279

Synonym: Obestatin (rat)

Synonym: CP-671906-01,UNII-GLZ1WA47Q8

Enterostatin(human,mouse,rat)

TP1835

Synonym: Enterostatin, human, mouse, rat

Target:

Peptide YY (human) (trifluoroacetate salt)

T35631

Synonym: Peptide Tyrosine Tyrosine

Target: GPR, Melanin-concentrating Hormone Receptor (MCHR)

C108297

T26935

Synonym: C-108297,C 108297

Synonym: HMR 1426,HMR1426

Synonym: Human orexin B

Synonym: KDS-5104,AM 3102,Methyl oleoylethanolamide

BMS-604992 dihydrochloride

T38959

Synonym: EX-1314 dihydrochloride,BMS-604992 dihydrochloride

Target:

BMS-604992 free base

T40876

Synonym: BMS-604992 free base,EX-1314 free base

Target:

2,5-Anhydro-D-mannitol

Synonym: BigLEN (mouse)

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide

TP1963

Synonym: cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide,[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide

Target:

Prolactin-Releasing Peptide (1-31) (rat)

T81390

Synonym:

Target:

[D-Phe12,Leu14]-Bombesin

TP1916

Synonym:

Target:

4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid

Synonym: CCK-33(human),Cholecystokinin-33(human)

Glucagon-like peptide 1 (1-37), human

TP1148

Synonym: HuGLP-1

Target:

Cat No.	Product Name	Synonyms	Targets
T12045	(-)-Hydroxycitric acid lactone	Garcinia lactone	ATP Citrate Lyase
	(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloac...		ATP Citrate Lyase
T0948L	Corticosterone	17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)	Glucocorticoid Receptor , Endogenous Metabolite
	Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stres...		Glucocorticoid Receptor , Endogenous Metabolite
T9297	Perseitol		Others
	Perseitol is a sugar that is specific to avocado honey. Perseitol have recently been reported as candidate biomarkers for avocado intake.		Others
TN6764	Simmondsin		Others
	Simmondsin is a natural product from Simmondsia chinensis -- jojoba. It reduced food intake and body weight without apparent negative effects in rats.		Others
TN1740	Homoeriodictyol		5-HT Receptor , transporter , Sodium Channel , Drug Metabolite
	Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotoni...
T11590	(-)-Hydroxycitric acid	Garcinia acid	ATP Citrate Lyase
	(-)-Hydroxycitric acid (Garcinia acid) (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia. It is a potent and competitive inhibitor of ATP citrate lyase. (-)-Hydroxycitric acid suppresses fatty aci...		ATP Citrate Lyase
T3727	Methyl syringate	Syringic Acid Methyl Ester	TRP/TRPV Channel
	Methyl syringate (Syringic Acid Methyl Ester) has a unique inhibitory activity toward aflatoxin production with a different mode of action from that of gallic acid. Methyl syringate from K. pictus is a specific and selec...		TRP/TRPV Channel
T2P2923	Stearic acid	Isostearic acid,Octadecanoic acid,Cetylacetic acid	Phosphatase , Endogenous Metabolite
	1. Stearic acid (Cetylacetic acid) can reduce metastatic tumor burden. 2. Stearic acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes. 3. Stearic acid and its derivatives have...		Phosphatase , Endogenous Metabolite
T4903	Heptadecanoic acid		Others , Endogenous Metabolite
	Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many "odd" length long chain amino acids are derived from the consumption of dairy fats (milk and meat). Heptadecanoic acid constitutes 0.61% o...		Others , Endogenous Metabolite
T4877	L-Homocystine		Endogenous Metabolite
	Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an ele...		Endogenous Metabolite
T13752	L-(+)-Arabinose		Endogenous Metabolite
	L-(+)-Arabinose selectively inhibits intestinal sucrase activity in a non-competitive manner, inhibiting glucose elevation caused by sucrose intake.		Endogenous Metabolite
TN1751	Hydroxycitric acid		ERK , p38 MAPK , Fatty Acid Synthase
	(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyas...		ERK , p38 MAPK , Fatty Acid Synthase

Natural Products

(-)-Hydroxycitric acid lactone

T12045

Synonym: Garcinia lactone

Target: ATP Citrate Lyase

Corticosterone

T0948L

Synonym: 17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)

Target: Glucocorticoid Receptor, Endogenous Metabolite

Target: 5-HT Receptor, transporter, Sodium Channel, Drug Metabolite

(-)-Hydroxycitric acid

T11590

Synonym: Garcinia acid

Target: ATP Citrate Lyase

Methyl syringate

T3727

Synonym: Syringic Acid Methyl Ester

Target: TRP/TRPV Channel

Stearic acid

T2P2923

Synonym: Isostearic acid,Octadecanoic acid,Cetylacetic acid

Target: Phosphatase, Endogenous Metabolite

Heptadecanoic acid

T4903

Synonym:

Target: Others, Endogenous Metabolite

L-Homocystine

T4877

Synonym:

Target: Endogenous Metabolite

L-(+)-Arabinose

T13752

Synonym:

Target: Endogenous Metabolite

Hydroxycitric acid

TN1751

Synonym:

Target: ERK, p38 MAPK, Fatty Acid Synthase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01369	AGRP Protein, Human, Recombinant (His)	Human	HEK293
	Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist ...
TMPY-04699	GAD65 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Glutamate decarboxylase 2, also known as glutamate decarboxylase 65 kDa isoform, 65 kDa glutamic acid decarboxylase, GAD2 and GAD65, is a member of thegroup II decarboxylase family. GAD2 is identified as a major autoanti...
TMPY-00875	Leptin Protein, Human, Recombinant	Human	E. coli
	Leptin is one of the most important hormones secreted by adipocytes, as an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine, and pro-inflammatory immu...
TMPH-02298	Urocortin-3 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
TMPY-00661	AGRP Protein, Human, Recombinant (hFc)	Human	HEK293
	Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist ...
TMPY-00630	AGRP Protein, Rhesus, Recombinant (mFc)	Rhesus	HEK293
	Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist ...
TMPJ-00743	PPY Protein, Human, Recombinant (His)	Human	Human Cells
	PPY belongs to the NPY family and is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknow...
TMPY-00434	AGRP Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist ...
TMPY-02269	AGRP Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist ...
TMPH-02522	GHRL Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid se...
TMPK-01319	GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi)	Cynomolgus	HEK293
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-01053	GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-01060	GFRAL/GFR alpha-like Protein, Human, Recombinant (hFc)	Human	HEK293
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-01058	GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi)	Human	HEK293
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-00284	ANGPTL3 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the li...
TMPK-01059	GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-01052	GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-01320	GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated	Cynomolgus	HEK293
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPJ-00606	Leptin Protein, Carassius auratus, Recombinant (His)	Carassius auratus	Yeast
	Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. In mammals, leptin ...
TMPK-00285	ANGPTL3 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the li...
TMPY-01590	GAD65 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	Glutamate decarboxylase 2, also known as glutamate decarboxylase 65 kDa isoform, 65 kDa glutamic acid decarboxylase, GAD2 and GAD65, is a member of thegroup II decarboxylase family. GAD2 is identified as a major autoanti...
TMPY-03515	GAD65 Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	Glutamate decarboxylase 2, also known as glutamate decarboxylase 65 kDa isoform, 65 kDa glutamic acid decarboxylase, GAD2 and GAD65, is a member of thegroup II decarboxylase family. GAD2 is identified as a major autoanti...
TMPJ-01061	Nucleobindin-2 Protein, Human, Recombinant	Human	E. coli
	Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulat...
TMPY-00286	Neuropeptide Y Protein, Human, Recombinant (hFc)	Human	HEK293
	NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ...
TMPJ-00052	Leptin Protein, Mouse, Recombinant	Mouse	E. coli
	Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have ...
TMPJ-00411	LEPR Protein, Human, Recombinant (hFc)	Human	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPJ-00977	LEPR Protein, Mouse, Recombinant (mFc)	Mouse	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPJ-00975	LEPR Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPJ-00976	LEPR Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPH-03256	CNR1 Protein, Rat, Recombinant (His)	Rat	in vitro E. coli expression system
	G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effe...
TMPH-01035	CNR1 Protein-VLP, Human, Recombinant (His)	Human	HEK293
	G-protein coupled receptor for endogenous cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG), as well as phytocannabinoids, such as delta(9)-tetrah...
TMPY-06375	Leptin Protein, Mouse, Recombinant (mFc)	Mouse	HEK293
	Leptin is one of the most important hormones secreted by adipocytes, as an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine, and pro-inflammatory immu...