Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 30.00 | |
2 mg | In stock | $ 40.00 | |
5 mg | In stock | $ 61.00 | |
10 mg | In stock | $ 85.00 | |
25 mg | In stock | $ 165.00 | |
50 mg | In stock | $ 298.00 | |
100 mg | In stock | $ 537.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 61.00 |
Description | (E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor. |
Kinase Assay | Human sRAGE is immobilized (10 μg/mL) overnight at 4°C in 96-well microtiter plates and blocked with 3% bovine serum albumin. 125I-labeled Aβ40, HMGB1, or S100B at 5 nM in the absence and presence of various concentrations of FPS2 or FPS-ZM1 (10 to 1,000 nM) is added to the wells containing immobilized sRAGE and incubated for 1 hour at room temperature in PBS. Wells are washed with cold PBS to remove unbound radiolabeled ligands, and the radioactivity is analyzed[1]. |
Synonyms | 3PO |
Molecular Weight | 210.23 |
Formula | C13H10N2O |
CAS No. | 13309-08-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (142.7 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(E)-3PO 13309-08-5 Metabolism Glucokinase (E)3PO 3PO (E) 3PO inhibitor inhibit