Shopping Cart
- Remove All
Your shopping cart is currently empty
σ1 Receptor antagonist-1
🥰Excellent
Catalog No. T9244Cas No. 1204401-49-9
σ1 Receptor antagonist-1 is a selective σ1 receptor antagonist.
σ1 Receptor antagonist-1
🥰Excellent
Purity: 99.80%
Catalog No. T9244Cas No. 1204401-49-9
σ1 Receptor antagonist-1 is a selective σ1 receptor antagonist.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | 30 € | In Stock | |
| 5 mg | 47 € | In Stock | |
| 10 mg | 76 € | In Stock | |
| 25 mg | 164 € | In Stock | |
| 50 mg | 268 € | In Stock | |
| 100 mg | 391 € | In Stock | |
| 200 mg | 562 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 51 € | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "σ1 Receptor antagonist-1"
Amitriptyline hydrochloride
Tryptizol, Domical, Annoyltin, Amitriptyline HCl
T0678549-18-8
Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
5-HT ReceptorAChRAdrenergic ReceptorHistamine ReceptorNorepinephrineSerotonin TransporterSigma receptorSodium ChannelTrk receptor
- 42 €
Size
QTY
Sigma-1 receptor antagonist 1
T129101639220-19-1
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity and can be used in the treatment of neuropathic pain studies.
- 55 €
Size
QTY
Cutamesine dihydrochloride
SA4503 dihydrochloride, SA4503 (dihydrochloride), AGY94806 dihydrochloride
T3597165377-44-6
Cutamesine dihydrochloride (SA4503 dihydrochloride) is a selective σ1 receptor agonist (IC50: 17.4 nM). It shows selectivity for σ1 over σ2 receptors, and inhibits angiotensin II-induced cardiomyocyte hypertrophy in vitro and attenuates myocardial hypertrophy in vivo. In a rat model of experimental stroke, it enhances brain plasticity and sensorimotor function.
- 35 €
Size
QTY
Ditolylguanidine
DTG, Di-o-tolylguanidine, 1,3-Di-o-tolylguanidine
T596997-39-2
Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).
- 28 €
Size
QTY
Glycerol phenylbutyrate
HPN-100
T15393611168-24-2
Glycerol phenylbutyrate (HPN-100) (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
- 37 €
Size
QTY
Opipramol
G-33040, G33040, Ensidon
T61376315-72-0In house
Opipramol (Ensidon) is a compound with antidepressant activity that attenuates cocaine-seeking behavior in a rat model of self-administration.Opipramol is a sigma (σ) receptor agonist with anxiolytic activity and may be used in the study of neurological disorders.
- 91 €
Size
QTY
S1R agonist 2
T72059150085-21-5In house
S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
- 37 €
Size
QTY
AB21 HCl
T77340L
AB21 HCl is a selective antagonist of the σ1 receptor, with Kis of 13 nM for σ1 receptor and 102 nM for σ2 receptor. AB21 HCl is known for its ability to reduce mechanical hypersensitivity.
- 185 €
Size
QTY
Blarcamesine hydrochloride
AVex-73 hydrochloride, Anavex 2-73, AE-37 hydrochloride
T4111195615-84-0
Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50: 860 nM).
- 36 €
Size
QTY
KSK67
T775932566715-93-1
KSK67 is a selective dual antagonist of sigma-2 and histamine H3 receptors with inhibitory effects on H3 receptors, sigma-1, and sigma-2 receptors, with Ki values of 3.2, 1531, and 101 nM, respectively.KSK67 can be used to study injury pain and neuropathic pain.
- 64 €
Size
QTY
KB-5492 free base
T62396113594-64-2In house
KB-5492 free base is an orally available and selective antiulcer agent that inhibits sigma receptors, inhibits [3H]1,3-di(2-tolyl)guanidine (DTG) binding to sigma receptors, and may be useful in the study of gastric lesions and gastric secretion.
- 33 €
Size
QTY
4-PPBP maleate
T22513201216-39-9
4-PPBP maleate is a potent σ1 receptor (ligand) agonist and a selective, non-competitive NR1a/2B NMDA receptor antagonist in the context of Xenopus oocytes expression, with neuroprotective properties.
- 38 €
Size
QTY
Select Batch
Purity:99.80%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | σ1 Receptor antagonist-1 is a selective σ1 receptor antagonist. |
| In vitro | σ1 Receptor antagonist-1 (compound 9) (10 μM; 48 hours) arrests cell cycle at G0/G1 phase to inhibit cell growth, and induces?apoptosis?of MCF-7/ADR cells[1] |
| Molecular Weight | 337.48 |
| Formula | C21H23NOS |
| Cas No. | 1204401-49-9 |
| Smiles | O=C1CC(Sc2ccccc12)C1CCN(Cc2ccccc2)CC1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90 mg/mL (266.68 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy σ1 Receptor antagonist-1 | purchase σ1 Receptor antagonist-1 | σ1 Receptor antagonist-1 cost | order σ1 Receptor antagonist-1 | σ1 Receptor antagonist-1 chemical structure | σ1 Receptor antagonist-1 in vitro | σ1 Receptor antagonist-1 formula | σ1 Receptor antagonist-1 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.