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(R)-(-)-Ibuprofen
🥰Excellent
Catalog No. T17309Cas No. 51146-57-7
Alias levibuprofen, (R)-Ibuprofen
(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive effects.
(R)-(-)-Ibuprofen
🥰Excellent
Purity: 99.47%
Catalog No. T17309Alias levibuprofen, (R)-IbuprofenCas No. 51146-57-7
(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive effects.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $42 | In Stock | |
| 100 mg | $59 | In Stock | |
| 200 mg | $87 | In Stock | |
| 500 mg | $143 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $96 | In Stock |
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Purity:99.47%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | (R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive effects. |
| In vitro | (R)-(-)-Ibuprofen participates in lipid metabolism pathways and integrates into triglycerides alongside endogenous fatty acids. It inhibits NF-κB luciferase activity (IC50: 121.8 μM), less potently than S(+)-ibuprofen (IC50: 61.7 μM). At 1 μM, it significantly reduces NF-κB activation and completely prevents its induction at 10 μM. Additionally, (R)-(-)-Ibuprofen (10 mM) does not affect HSF [1][2]. |
| Alias | levibuprofen, (R)-Ibuprofen |
| Molecular Weight | 206.28 |
| Formula | C13H18O2 |
| Cas No. | 51146-57-7 |
| Smiles | CC(C)Cc1ccc(cc1)[C@@H](C)C(O)=O |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (218.15 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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