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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $42 | In Stock | |
100 mg | $59 | In Stock | |
200 mg | $87 | In Stock | |
500 mg | $143 | In Stock | |
1 mL x 10 mM (in DMSO) | $96 | In Stock |
Description | (R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive effects. |
In vitro | (R)-(-)-Ibuprofen is involved in pathways of lipid metabolism and is incorporated into triglycerides along with endogenous fatty acids. (R)-(-)-Ibuprofen inhibits NF-κB luciferase activity (IC50: 121.8 μM), weaker than that of S(+)-ibuprofen (IC50, 61.7 μM). (R)-(-)-Ibuprofen (1 μM) significantly decreases NF-κB activation and fully prevents NF-κB induction at 10 μM. Furthermore, (R)-(-)-Ibuprofen (10 mM) has no effect on HSF [1][2]. |
Alias | levibuprofen, (R)-Ibuprofen |
Molecular Weight | 206.28 |
Formula | C13H18O2 |
Cas No. | 51146-57-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (218.15 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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