ibuprofen

Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes.

(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive effects.

Ibuprofen diethylaminoethyl ester (BF DEAE) has anti-inflammatory activity, acts as a local anaesthetic and can be used in the study of neurological disorders.

Ibuprofen Piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.Ibuprofen piconol is a Pyridyl ester of ibuprofen.

Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.

Ibuprofen-d2 is a deuterated compound of Ibuprofen. Ibuprofen has a CAS number of 15687-27-1. Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes.

(S)-(+)-Ibuprofen D3 is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen ,it is an inhibitor of COX-1 and COX-2 activity (IC50s of 2.1 μM and 1.6 μM).

Ibuprofen Impurity K is a compound that serves as an impurity in Ibuprofen. Ibuprofen itself is an anti-inflammatory inhibitor specifically designed to target COX-1 and COX-2. It exhibits inhibitory activity with IC50 values of 13 μM and 370 μM for COX-1 and COX-2, respectively.

Ibuprofen alcohol, a nonsteroidal antiinflammatory drug (NSAID), exhibits very little activity for acid-sensing ion channels (ASICs).

Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective inhibitor of COX-1 (IC50 = 13 μM) that inhibits cell proliferation and angiogenesis, and induces cell apoptosis. It is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor, used in research on pain, swelling, inflammation, infection, immunology, and cancers [1] [2] [5] [8].

1-Oxo Ibuprofen is a useful organic compound for research related to life sciences. The catalog number is T41363 and the CAS number is 65813-55-0.

Ibuprofen ethyl ester is a derivative of Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) that is known to inhibit PGH synthase-1 and PGH synthase-2.

Ibuprofen D3 is a deuterium labeled Ibuprofen. Ibuprofen is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM).

(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).

Ibuprofen Methyl Ester-d2 is a deuterated compound of Ibuprofen Methyl Ester. Ibuprofen Methyl Ester has a CAS number of 61566-34-5.

2-Hydroxy Ibuprofen, a metabolite of Ibuprofen, an anti-inflammatory inhibitor targeting COX-1 COX-2 (IC50s: 13 μM 370 μM).

1-Hydroxy Ibuprofen, a metabolite of Ibuprofen in P. australis[1], functions as an anti-inflammatory inhibitor specifically targeting COX-1 and COX-2, with inhibitory concentration 50 (IC50) values of 13 μM and 370 μM, respectively[1].

Ibuprofen Impurity F is a known impurity of Ibuprofen, which acts as an anti-inflammatory inhibitor that selectively targets both COX-1 and COX-2 enzymes. It exhibits inhibitory activity with IC50 values of 13 μM and 370 μM for COX-1 and COX-2, respectively.

Ibuprofen impurity 1 is a known impurity of Ibuprofen, an anti-inflammatory inhibitor that targets COX-1 and COX-2 with IC50 values of 13 μM and 370 μM, respectively[1].

Ibuprofen carboxylic acid is a major metabolite of ibuprofen . It prevents fructose-, cyanate-, and prednisolone-induced inactivation of catalase and fructose- and cyanate-induced inactivation of fumarase when used at a concentration of 2 mM and penetrates into the lens of isolated bovine eyes. Ibuprofen carboxylic acid has been found in bank filtrate and surface water, as well as influent and effluent wastewater, and is considered a micropollutant.

Ketoprofen (RP-19583) is a propionic acid derivative and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. It inhibits cyclo-oxygenase I and II, decreasing the formation of prostaglandin and thromboxane precursors. This reduction in prostaglandin synthesis, mediated by prostaglandin synthase, is responsible for its therapeutic effects. Additionally, Ketoprofen decreases thromboxane A2 formation via thromboxane synthase, inhibiting platelet aggregation.

3-AMINO-1,2,4-TRIAZINE is an aromatic bioactive compound. It has been used to synthesize a variety of drugs, including the antifungal drug fluconazole, the anti-inflammatory drug ibuprofen and the anticancer drug paclitaxel. It has also been used in the design of new drugs, such as the anti-AIDS drug zidovudine and the anti-malarial drug artemisinin.

4-Butoxyphenol (P-Butoxyphenol) is a phenolic compound with a wide range of applications in science and industry. It is often used in the synthesis of other compounds such as 4-butoxyphenylacetic acid and 4-butoxyphenylacetonitrile. It is also used in the synthesis of drugs such as ibuprofen and naproxen.

Zoliprofen is a potent and orally available non-steroidal anti-inflammatory agent with anti-inflammatory, antipyretic and analgesic activity, and inhibits carobolin, mycobacterium, and knife-ball protein A-induced rat paw oedema, as well as anti-rat serum-induced fracture or dorsal skin oedema. Zoliprofen is 20 times more effective than ibuprofen and fenoprofen against collagen- or arachidonic acid-induced platelet aggregation in rats and rabbits. Zoliprofen was 20 times more effective than ibuprofen and fenoprofen in inhibiting endotoxin-induced diarrhoea in mice and arachidonic acid-induced acute mortality in rabbits.

Dexibuprofen (S-ibuprofen) is a non-steroidal anti-inflammatory drug. Most ibuprofen preparations contain a racemic mixture of two isomers. Dexibuprofen as a cyclooxygenase inhibitor.

(-)-Ibuprofenamide, an amide prodrug of Ibuprofen, exhibits anti-inflammatory activity.

Naproxen ethyl ester is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a non-selective COX inhibitor.

1,3-Distearoyl glycerol, a diacylglycerol with stearic acid at the sn-1 and sn-3 positions, is present in wheat bran extract. It is utilized in creating prodrug versions of NSAIDs (ibuprofen, naproxen, and diclofenac) with decreased ulcerogenicity.

Suprofen (Suprol) is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.

ATV041, an orally active compound that combines features of Ibuprofen and nucleotide analogues, enhances the oral pharmacokinetic (PK) profile and tissue distribution, exhibiting anti-mouse hepatitis virus (MHV) activity. The compound demonstrates a dose-dependent reduction in viral load, tissue damage, and virus-induced inflammation [1].

Naproxen glucuronide is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a nonselective COX inhibitor.

Parecoxib is a cyclooxygenase-2 inhibitor used for the short-term treatment of postoperative pain in adults. Parecoxib is a water-soluble and injectable prodrug of valdecoxib. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib and r

5-Methoxycanthin-6-one displays moderate cytotoxic activity against the human prostate cancer cell PC-3 line, with IC50 values ranging from 13.5-15.4 uM versus doxorubicine with IC50 = 1.5 uM. It also exhibits a clear suppressive effect on the phagocytosi