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6-Methoxytricin
🥰Excellent
Catalog No. T10183Cas No. 76015-42-4
6-Methoxytricin, a flavonoid isolated from Centella asiatica, is an inhibitor of aldose reductase (AR) and advanced glycosylation end-products (AGE), and inhibits T-cell proliferation and activation in biologic cells.
6-Methoxytricin
🥰Excellent
Purity: 99.4%
Catalog No. T10183Cas No. 76015-42-4
6-Methoxytricin, a flavonoid isolated from Centella asiatica, is an inhibitor of aldose reductase (AR) and advanced glycosylation end-products (AGE), and inhibits T-cell proliferation and activation in biologic cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $65 | In Stock | |
| 2 mg | $92 | In Stock | |
| 5 mg | $150 | In Stock | |
| 10 mg | $267 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $200 | In Stock |
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Purity:99.4%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | 6-Methoxytricin, a flavonoid isolated from Centella asiatica, is an inhibitor of aldose reductase (AR) and advanced glycosylation end-products (AGE), and inhibits T-cell proliferation and activation in biologic cells. |
| Targets&IC50 | AR:30.29 μM, AGE:134.88 μM |
| In vitro | 6-Methoxytricin has a significant inhibitory effect on T cell proliferation induced by concanavalin A (Con A), with an IC50 value of 1.4 μM [2]. |
| Molecular Weight | 360.31 |
| Formula | C18H16O8 |
| Cas No. | 76015-42-4 |
| Smiles | O=C1C=C(OC2=CC(O)=C(OC)C(O)=C12)C=3C=C(OC)C(O)=C(OC)C3 |
| Relative Density. | 1.461 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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