Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bay K 8644 (SQ 28,873) is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 263.00 | |
50 mg | In stock | $ 416.00 | |
100 mg | In stock | $ 618.00 |
Description | Bay K 8644 (SQ 28,873) is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM. |
Targets&IC50 | Ca2+ channel, L-type:17.3nM(EC50) |
In vitro | Bay K 8644 increases resting tension in segments of mesenteric arteries isolated from young and old rats as an agonist of L-type Ca2+ channel[2] |
In vivo | Bay K 8644 induces small contractions in aortae from Wistar-Kyoto(WKY) rats of 5-week-, 3-month-, 1-year-, 1.5-year-old, which are unaltered with age.[3] |
Synonyms | (±)-BAY-K-8644, SQ 28,873 |
Molecular Weight | 356.3 |
Formula | C16H15F3N2O4 |
CAS No. | 71145-03-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 35.6 mg/mL (100 mM)
You can also refer to dose conversion for different animals. More
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Bay K 8644 71145-03-4 Membrane transporter/Ion channel Metabolism Calcium Channel (±)-BAY-K-8644 BAY-K 8644 BAY-K8644 influx L-type inhibit sarcolemmal Ca2+ channels Bay K-8644 (±)-Bay K 8644 Inhibitor Bay K8644 BAY-K-8644 SQ 28,873 Ca channels Ca2+ inhibitor