Shopping Cart
- Remove All
![TargetMol](https://newstatic.targetmol.com/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $139 | In Stock | |
5 mg | $297 | In Stock | |
10 mg | $447 | In Stock | |
25 mg | $739 | In Stock | |
50 mg | $987 | In Stock | |
100 mg | $1,390 | In Stock | |
1 mL x 10 mM (in DMSO) | $327 | In Stock |
Description | Binodenoson (WRC 0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging[1]. |
In vitro | 2-(cyclohexylmethylidenehydrazino)adenos (30-300 nM) decreases oxidative activity of tumor necrosis factor-α–primed FMLP-stimulated polymorphonuclear leukocytes in human whole blood and acts synergistically with Rolipram[1]. |
In vivo | The compound 2-(cyclohexylmethylidenehydrazino)adenos, administered at dosages ranging from 0-0.9 μg/kg/h to adult Wistar rats in a bacterial meningitis model, either alone or combined with rolipram (0-0.01 μg/kg/h), effectively suppresses pleocytosis and mitigates the lipopolysaccharide-induced elevation in blood-brain barrier permeability (BBBP). This suggests a reduction in neutrophil-induced damage[1]. |
Alias | WRC 0470, MRE-0470, 2-(cyclohexylmethylidenehydrazino)adenos |
Molecular Weight | 391.42 |
Formula | C17H25N7O4 |
Cas No. | 144348-08-3 |
Storage | keep away from direct sunlight,store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||
Solubility Information | DMSO: 11 mg/mL (28.1 mM) ![]() | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.