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Bismuth Subsalicylate

Catalog No. T0424 CAS 14882-18-9

Synonyms: Bismuth subsalicylat, Bismuth(III) salicylate basic, Bismuth oxysalicylate

Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.

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Bismuth Subsalicylate Chemical Structure

Bismuth Subsalicylate, CAS 14882-18-9

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5 g	In stock	$ 48.00
10 g	Inquiry	$ 89.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Purity: 99.87%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
In vivo	In the gastrointestinal tract, Bismuth Subsalicylate is metabolized into salicylic acid and insoluble bismuth salts. It exhibits an inhibitory effect on Prostaglandin G/H Synthase 1/2 (cyclooxygenase-1/2, COX-1/2), thereby reducing inflammation/irritation of the gastric and intestinal mucosa.

Synonyms	Bismuth subsalicylat, Bismuth(III) salicylate basic, Bismuth oxysalicylate
Molecular Weight	362.09
Formula	C7H5BiO4
CAS No.	14882-18-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 27.5 mg/ml (75.95 mM)

H2O: Insoluble

References and Literature

1. Sox TE, et al. Antimicrob Agents Chemother, 1989, 33(12), 2075-2082. 2. Bierer DW. Rev Infect Dis, 1990, 12 Suppl 1:S3-8.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Bioactive Compounds Library Max Clinical Compound Library Anti-Aging Compound Library Neuronal Signaling Compound Library Human Metabolite Library Anti-Pancreatic Cancer Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Bismuth Subsalicylate 14882-18-9 Immunology/Inflammation Neuroscience PGE Synthase COX sick Inhibitor inhibit Prostaglandin E synthase inflammation Bismuth subsalicylat Bismuth(III) salicylate basic nausea,?salicylate PGE synthase Bismuth oxysalicylate acid reflux,?indigestion,?diarrhoea antacid heartburn inhibitor

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