Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDK9-IN-2 is a special CDK9 inhibitor and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours) and H929 multiple myeloma cell line (72 hours), respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 80.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 296.00 | |
25 mg | In stock | $ 512.00 | |
50 mg | In stock | $ 743.00 | |
100 mg | In stock | $ 1,050.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 217.00 |
Description | CDK9-IN-2 is a special CDK9 inhibitor and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours) and H929 multiple myeloma cell line (72 hours), respectively. |
Targets&IC50 | CDK9:5 nM, H929 multiple myeloma cell lines: |
In vitro | CDK9-IN-2, at a concentration of 200 nM, decreases MEPCE expression, suggesting MEPCE serves as a pharmacodynamic indicator for CDK9 inhibitors. Moreover, MCL1 protein levels are diminished within 2 hours of CDK9-IN-2 treatment, with further reduction observed after 16 hours of exposure to a higher concentration of 500 nM. |
Molecular Weight | 425.93 |
Formula | C23H25ClFN5 |
CAS No. | 1263369-28-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (117.39 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CDK9-IN-2 1263369-28-3 Cell Cycle/Checkpoint Others CDK inhibit Inhibitor Cyclin dependent kinase CDK9IN2 CDK9 IN 2 CDK-9-IN-2 inhibitor