Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 448.00 | |
10 mg | In stock | $ 658.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,380.00 | |
100 mg | In stock | $ 1,890.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 479.00 |
Description | CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM. |
Targets&IC50 | 3D7 strain:51 nM , DD2 strain:53 nM |
In vivo | In P. chabaudi ASS-infected mice, oral administration of CWHM-1552 inhibits parasitemia at 99.9% and 94% at doses of 30 mg/kg and 10 mg/kg, respectively. In KM mice, intravenous injection of CWHM-1552 (2 mg/kg) shows a T1/2 of 2.7 h and low clearance[1]. |
Molecular Weight | 387.47 |
Formula | C22H27F2N3O |
CAS No. | 2368253-58-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (141.94 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CWHM-1552 2368253-58-9 Microbiology/Virology Parasite CWHM 1552 CWHM1552 inhibitor inhibit