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Cbz-B3A
Catalog No. T14886Cas No. 1884710-81-9
Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks translation by 68%.
Cbz-B3A
Purity: 98.63%
Catalog No. T14886Cas No. 1884710-81-9
Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks translation by 68%.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $108 | In Stock | |
| 2 mg | $158 | In Stock | |
| 5 mg | $265 | In Stock | |
| 10 mg | $395 | In Stock | |
| 25 mg | $648 | In Stock | |
| 50 mg | $890 | In Stock | |
| 100 mg | $1,220 | In Stock |
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Purity:98.63%
ee:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks translation by 68%. |
| In vitro | Cbz-B3A (10 μM) inhibits the phosphorylation of 4EBP1 and p70S6k Thr-389 [1]. |
| Molecular Weight | 706.87 |
| Formula | C35H58N6O9 |
| Cas No. | 1884710-81-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (14.14 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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