Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the expression of iNOS mRNA and LPS-induced mRNA expression of TNFα and CCL2. Cearoin induces autophagy, ERK activation and apoptosis in neuroblastoma SH-SY5Y cells, which is mediated primarily by ROS generation, suggesting its therapeutic application for the treatment of neuroblastomas.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 524.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 550.00 |
Description | Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the expression of iNOS mRNA and LPS-induced mRNA expression of TNFα and CCL2. Cearoin induces autophagy, ERK activation and apoptosis in neuroblastoma SH-SY5Y cells, which is mediated primarily by ROS generation, suggesting its therapeutic application for the treatment of neuroblastomas. |
Source |
Molecular Weight | 244.24 |
Formula | C14H12O4 |
CAS No. | 52811-37-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Cearoin 52811-37-7 Apoptosis Chromatin/Epigenetic DNA Damage/DNA Repair Immunology/Inflammation MAPK NF-Κb Proteases/Proteasome Caspase ROS NF-κB TNF PARP IκB/IKK BCL ERK inhibitor inhibit