Shopping Cart
- Remove All
Your shopping cart is currently empty
Crinecerfont
🥰Excellent
Catalog No. T31095Cas No. 752253-39-7
Alias SSR-125543A, SSR125543A, SSR-125543, SSR125543, SSR 125543A, SSR 125543
Crinecerfont (SSR-125543) is a selective antagonist of corticotropin-releasing factor 1 receptor (CRF1) and can be used in studies about Classic congenital adrenal hyperplasia.
Crinecerfont
🥰Excellent
Purity: 99.10%
Catalog No. T31095Alias SSR-125543A, SSR125543A, SSR-125543, SSR125543, SSR 125543A, SSR 125543Cas No. 752253-39-7
Crinecerfont (SSR-125543) is a selective antagonist of corticotropin-releasing factor 1 receptor (CRF1) and can be used in studies about Classic congenital adrenal hyperplasia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 111 € | In Stock | |
| 2 mg | 166 € | In Stock | |
| 5 mg | 255 € | In Stock | |
| 10 mg | 375 € | In Stock | |
| 25 mg | 562 € | In Stock | |
| 50 mg | 792 € | In Stock | |
| 100 mg | 1.064 € | In Stock | |
| 500 mg | 2.147 € | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Crinecerfont"
4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine
T601262649012-21-3In house
4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagonist with Ki = 1.0 nM for human CRF-R1.
- 111 €
Size
QTY
CP 316311
T15008175139-41-0In house
CP 316311 is a specific CRF1 receptor antagonist with potential antidepressant activity and may be used in the study of depression.
- 278 €
Size
QTY
CP 376395
CP-316311
T4329175140-00-8
CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.
- 33 €
Size
QTY
K 41498 aceate
TP2009L
K41498 acetate, an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. K41498 acetate is a potent and highly selective antagonist CRF2 receptor with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively.
- 321 €
Size
QTY
Astressin acetate
Astressin acetate (170809-51-5 Free base)
TP1448L
Astressin acetate is an antagonist of corticotropin releasing factor (CRF) with low affinity for the CRF binding protein and high affinity for the cloned pituitary receptor(Ki = 2 nM).
- 224 €
Size
QTY
Corticotropin-releasing factor (human) acetate
Corticotropin-releasing factor (human) acetate (86784-80-7 Free base)
TP1144L
Corticotropin-releasing factor (human) acetate stimulates to synthesize and secret adrenocorticotropin in the anterior pituitary.
- 140 €
Size
QTY
Urocortin (rat) acetate
Urocortin (rat) acetate (171543-83-2 Free base)
TP1020L
Urocortin (rat) acetate is an agonist of endogenous CRFR with Kis of 13 nM, 1.5 nM, and 0.97 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively. Urocortin (rat) acetate is a neuropeptide.
- 151 €
Size
QTY
Tildacerfont
T262781014983-00-6
Tildacerfont is an antagonist of CRF1 and reduces the levels of adrenocorticotropic hormone and adrenal androgen. Tildacerfont can be used in studies about congenital adrenal hyperplasia.
- 27 €
Size
QTY
CRF (6-33) acetate(120066-38-8 free base)
TP2047L
CRF (6-33) acetate is a corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo.
- 354 €
Size
QTY
Antalarmin hydrochloride
T22577220953-69-5
Antalarmin hydrochloride is an antagonist of corticotropin-releasing factor 1(CRF1). Antalarmin hydrochloride produces anti-inflammatory effects and suppresses stress-induced gastric ulceration related to irritable bowel syndrome.
- 55 €
Size
QTY
Verucerfont
NBI77860, GSK561679
T7361885220-61-1
Verucerfont (NBI77860) is an antagonist of corticotropin-releasing factor receptor 1 (CRF1) .
- 55 €
Size
QTY
α-helical CRF 9-41 acetate
α-helical CRF 9-41 acetate(90880-23-2 Free base)
TP2048L
α-helical CRF 9-41 acetate is a competitive antagonist of CRF2 (KB = 100 nM) and a partial agonist of CRF1 (EC50 = 140 nM).
- 208 €
Size
QTY
Select Batch
Purity:99.10%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Crinecerfont (SSR-125543) is a selective antagonist of corticotropin-releasing factor 1 receptor (CRF1) and can be used in studies about Classic congenital adrenal hyperplasia. |
| Alias | SSR-125543A, SSR125543A, SSR-125543, SSR125543, SSR 125543A, SSR 125543 |
| Molecular Weight | 483.04 |
| Formula | C27H28ClFN2OS |
| Cas No. | 752253-39-7 |
| Smiles | [C@H](N(CC#C)C1=NC(=C(C)S1)C2=C(Cl)C=C(OC)C(C)=C2)(CC3CC3)C4=CC(F)=C(C)C=C4 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (93.16 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
| |||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Crinecerfont | purchase Crinecerfont | Crinecerfont cost | order Crinecerfont | Crinecerfont chemical structure | Crinecerfont formula | Crinecerfont molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.