Shopping Cart
- Remove All
Your shopping cart is currently empty
Argentina
Australia
Austria
Belgium
Brazil
Bulgaria
Croatia
Cyprus
Czech
Denmark
Egypt
Estonia
Finland
France
Germany
Greece
Hong Kong
Hungary
Iceland
India
Ireland
Israel
Italy
Japan
Korea
Latvia
Lebanon
Malaysia
Malta
Morocco
Netherlands
New Zealand
Norway
Poland
Portugal
Romania
Singapore
Slovakia
Slovenia
Spain
Sweden
Switzerland
Taiwan,China
Thailand
Turkey
United Kingdom
United States
Other Countries
Select your Country or Region
EL-102
Catalog No. T15205Cas No. 1233948-61-2
EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $89 | In Stock | |
| 5 mg | $228 | In Stock | |
| 10 mg | $368 | In Stock | |
| 25 mg | $573 | In Stock | |
| 50 mg | $778 | In Stock | |
| 100 mg | $1,160 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $193 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "EL-102"
Myoseverin
T21632267402-71-1
Myoseverin, an inducer of the reversible fission of multinucleated myotubes into mononucleated fragments, affecting the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and stress response genes, consistent with
- $66
Size
QTY
Tubulin inhibitor 6
T13224105925-39-1
Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.
- $32
Size
QTY
CCB02
T107042100864-57-9In house
CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-related kinases, or the phosphorylation status of Aurora-A, CDK2, Plk1, Plk2, and CHK1.
- $117
Size
QTY
Zagotenemab
T767262019133-28-7
Zagotenemab is a humanized antibody against the microtubule-associated protein tau that selectively regulates tau deposits in the brain. Zagotenemab can be used to study neurological disorders such as Alzheimer's disease.
- $198
Size
QTY
AK301
T26585314022-97-4In house
AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM). Colon cancer cells arrested in mitosis with AK301 readily underwent a p53-dependent apoptosis following compound withdrawal and arrest release.
- $350
Size
QTY
Deoxypodophyllotoxin
TN108719186-35-7
Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities.
- $116
Size
QTY
CK-869
T5860388592-44-7
CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.
- $34
Size
QTY
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
T600411383373-65-6
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.
- $195
Size
QTY
Epothilone A
T6490152044-53-6
Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.
- $31
Size
QTY
Lys-SMCC-DM1
T119171281816-04-3
DM1 is a tubulin inhibitor. Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is the active metabolite of DM1.
- $289
Size
QTY
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer. |
| In vitro | In CWR22, 22Rv1, DU145, PC-3, DLKP, and doxorubicin-selected variant DLKPA cell lines, EL-102 (0-120 nM; 72 hours) inhibited cell proliferation with IC50 values of 24, 21.7, 40.3, 37.0, 14.4, and 16.3 nM, respectively[1]. |
| In vivo | In nude mice bearing CWR22 xenografts, EL-102 (oral gavage; 12 and 15 mg/kg; administered every 5 days with 2 days off) showed no effect on tumor growth but enhanced the effect of docetaxel on the tumor[1]. |
| Alias | EL102 |
| Molecular Weight | 384.47 |
| Formula | C19H16N2O3S2 |
| Cas No. | 1233948-61-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 20 mg/mL (52.02 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
| |||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。 Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Dose Conversion
You can also refer to dose conversion for different animals. More
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.