Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSK-LSD1 dihydrochloride (GSK-LSD1 2HCl) is a specificity irreversible LSD1 inhibitor (IC50: 16 nM). The selectivity of GSK-LSD1 for LSD1 is <1000 fold over other closely related FAD utilizing enzymes (i.e. MAO-A, LSD2, MAO-B).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 65.00 | |
10 mg | In stock | $ 105.00 | |
25 mg | In stock | $ 221.00 | |
50 mg | In stock | $ 335.00 | |
100 mg | In stock | $ 549.00 | |
500 mg | In stock | $ 1,170.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 65.00 |
Description | GSK-LSD1 dihydrochloride (GSK-LSD1 2HCl) is a specificity irreversible LSD1 inhibitor (IC50: 16 nM). The selectivity of GSK-LSD1 for LSD1 is >1000 fold over other closely related FAD utilizing enzymes (i.e. MAO-A, LSD2, MAO-B). |
Targets&IC50 | LSD1:16 nM |
In vitro | GSK-LSD1 induces gene expression changes in cancer cell lines with average EC50 of < 5 nM and inhibits cancer cell line growth with average EC50 of < 5 nM. [1] |
Synonyms | GSK-LSD1 (hydrochloride), GSK-LSD1 2HCl |
Molecular Weight | 289.24 |
Formula | C14H22Cl2N2 |
CAS No. | 2102933-95-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (86.43 mM)
H2O: 10 mg/mL (34.57 mM)
You can also refer to dose conversion for different animals. More
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GSK-LSD1 dihydrochloride 2102933-95-7 Chromatin/Epigenetic Histone Demethylase GSK LSD1 dihydrochloride GSK-LSD1 Dihydrochloride Monoamine Oxidase GSK-LSD-1 dihydrochloride Inhibitor GSK-LSD1 (hydrochloride) GSK-LSD1 2HCl inhibit MAO GSKLSD1 dihydrochloride GSK-LSD1 inhibitor