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IBT6A

Catalog No. T10625Cas No. 1022150-12-4

IBT6A, an impurity of Ibrutinib, is a Btk inhibitor (IC50: 0.5 nM) that can be utilized in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.

IBT6A

IBT6A

Purity: 99.88%
Catalog No. T10625Cas No. 1022150-12-4
IBT6A, an impurity of Ibrutinib, is a Btk inhibitor (IC50: 0.5 nM) that can be utilized in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.
Pack SizePriceAvailabilityQuantity
100 mg$42In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Purity:99.88%
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Product Introduction

Bioactivity
Description
IBT6A, an impurity of Ibrutinib, is a Btk inhibitor (IC50: 0.5 nM) that can be utilized in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.
Chemical Properties
Molecular Weight386.45
FormulaC22H22N6O
Cas No.1022150-12-4
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (64.69 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5877 mL12.9383 mL25.8766 mL129.3828 mL
5 mM0.5175 mL2.5877 mL5.1753 mL25.8766 mL
10 mM0.2588 mL1.2938 mL2.5877 mL12.9383 mL
20 mM0.1294 mL0.6469 mL1.2938 mL6.4691 mL
50 mM0.0518 mL0.2588 mL0.5175 mL2.5877 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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