Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 40.00 | |
10 mg | In stock | $ 57.00 | |
25 mg | In stock | $ 94.00 | |
50 mg | In stock | $ 138.00 | |
100 mg | In stock | $ 198.00 | |
200 mg | In stock | $ 297.00 | |
500 mg | In stock | $ 512.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 42.00 |
Description | Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes. |
In vitro | Indobufen suppresses TxA2 but not PGE2 synthesis in LPS-stimulated monocytes. Indobufen causes the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered. Indobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB2 levels. |
Synonyms | Ibustrin |
Molecular Weight | 295.33 |
Formula | C18H17NO3 |
CAS No. | 63610-08-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (846.51 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Indobufen 63610-08-2 Immunology/Inflammation Neuroscience COX Ibustrin Inhibitor inhibit Cyclooxygenase inhibitor