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Indobufen
🥰Excellent
Catalog No. T15577Cas No. 63610-08-2
Alias Ibustrin
Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.
Indobufen
🥰Excellent
Purity: 99.63%
Catalog No. T15577Alias IbustrinCas No. 63610-08-2
Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $30 | In Stock | |
| 25 mg | $47 | In Stock | |
| 50 mg | $68 | In Stock | |
| 100 mg | $95 | In Stock | |
| 500 mg | $235 | In Stock |
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Purity:99.63%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes. |
| In vitro | Indobufen suppresses TxA2 but not PGE2 synthesis in LPS-stimulated monocytes. Indobufen causes the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered. Indobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB2 levels. |
| Alias | Ibustrin |
| Molecular Weight | 295.33 |
| Formula | C18H17NO3 |
| Cas No. | 63610-08-2 |
| Smiles | O=C1N(CC=2C1=CC=CC2)C3=CC=C(C(C(O)=O)CC)C=C3 |
| Relative Density. | 1.275 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (186.23 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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