Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H: NQO1 as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 140.00 | |
2 mg | In stock | $ 197.00 | |
5 mg | In stock | $ 288.00 | |
10 mg | In stock | $ 449.00 | |
25 mg | In stock | $ 739.00 | |
50 mg | In stock | $ 987.00 | |
100 mg | In stock | $ 1,390.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 276.00 |
Description | KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H: NQO1 as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. |
Synonyms | NQO1 activator 1 |
Molecular Weight | 240.26 |
Formula | C14H12N2O2 |
CAS No. | 1800405-30-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 245 mg/mL (1019.73 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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KL1333 1800405-30-4 Metabolism Mitochondrial Metabolism NADPH Inhibitor KL-1333 inhibit KL 1333 NQO1 activator 1 inhibitor