-20℃ 3 years powder
-80℃ 2 years in solvent
KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM). It has not inhibitory for FAAH (IC50 > 50 μM). It also effectively and selectively blocks hydrolysis of 2-arachidonoylglycerol (2-AG) in mice (IC50: 2.5 nM, 2-AG; >50 μM, AEA).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | 60.00 | |
10 mg | In stock | 90.00 | |
25 mg | In stock | 195.00 | |
100 mg | In stock | 690.00 | |
1 mL * 10 mM (in DMSO) | In stock | 70.00 |
Description | KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM). It has not inhibitory for FAAH (IC50 > 50 μM). It also effectively and selectively blocks hydrolysis of 2-arachidonoylglycerol (2-AG) in mice (IC50: 2.5 nM, 2-AG; >50 μM, AEA). |
Targets&IC50 | MAGL, |
In vivo | DprE1-IN-2 has efficacy in a rodent model of tuberculosis. |
Appearance | solid |
Molecular Weight | 549.42 |
Formula | C24H21F6NO7 |
CAS No. | 1380424-42-9 |
-20℃ 3 years powder
-80℃ 2 years in solvent
DMSO: 10 mM
( < 1 mg/ml refers to the product slightly soluble or insoluble )
Safe and effective drug dosing is necessary, regardless of its purpose of administration. Learn More
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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.