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LJ570

Catalog No. T8374 CAS 2252488-69-8

LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)

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LJ570, CAS 2252488-69-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 248.00
2 mg	In stock	$ 375.00
5 mg	In stock	$ 577.00
10 mg	In stock	$ 826.00
25 mg	In stock	$ 1,260.00
50 mg	In stock	$ 1,680.00
100 mg	In stock	$ 2,290.00
500 mg	In stock	$ 4,590.00
1 mL * 10 mM (in DMSO)	In stock	$ 621.00

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Purity: 99.89%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)
Targets&IC50	PPARγ:0.12 μM (EC50), PPARα:1.05 μM (EC50)

Molecular Weight	394.46
Formula	C27H22O3
CAS No.	2252488-69-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 9 mg/mL (22.82 mM)

References and Literature

1. Antonio L , Luca P , Carmen C , et al. Identification of the First PPARα/γ Dual Agonist Able to Bind to Canonical and Alternate Sites of PPARγ and to Inhibit its Cdk5-Mediated Phosphorylation[J]. Journal of Medicinal Chemistry, 2018:acs.jmedchem.8b00835-.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Anti-Breast Cancer Compound Library Bioactive Compounds Library Max Anti-Hypertension Compound Library Anti-Diabetic Compound Library Transcription Factor-Targeted Compound Library Anti-Metabolism Disease Compound Library Lipid Metabolism Compound Library Metabolism Compound Library Anti-Pancreatic Cancer Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

LJ570 2252488-69-8 DNA Damage/DNA Repair Metabolism PPAR inhibit Peroxisome proliferator-activated receptors LJ 570 LJ-570 Inhibitor inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.