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MEDICA16

Catalog No. T22967 CAS 87272-20-6

Synonyms: MEDICA 16

MEDICA16 is a selective agonist for GPR40 as well as a partial agonist for GPR120. MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle with an increase in insulin sensitivity.

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MEDICA16, CAS 87272-20-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	MEDICA 16
Molecular Weight	342.51
Formula	C20H38O4
CAS No.	87272-20-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: Soluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Hara T, Hirasawa A, Sun Q, et al. Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch Pharmacol. 2009;380(3):247-255. 2. Atkinson LL, et al. MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma triacylglycerol levels in insulin-resistant JCR: LA-cp rats. Diabetes. 2002;51(5):1548-1555.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MEDICA16 87272-20-6 G蛋白偶联受体代谢内分泌与激素其他 GPR ATP Citrate Lyase Others ACLY antidiabetogenic antidiabetic skeletal Inhibitor ligands Free Fatty Acid Receptor MEDICA-16 insulin FFAR endogenous muscle MEDICA 16 inhibit inhibitor

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