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Merafloxacin
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Merafloxacin
Catalog No. T9066Cas No. 91188-00-0
Merafloxacin (CI 934) is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $56 | In Stock | |
| 2 mg | $79 | In Stock | |
| 5 mg | $122 | In Stock | |
| 10 mg | $198 | In Stock | |
| 25 mg | $363 | In Stock | |
| 50 mg | $539 | In Stock | |
| 100 mg | $778 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $133 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Merafloxacin (CI 934) is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2. |
| In vitro | Frameshift inhibition by merafloxacin is robust to mutations within the pseudoknot region and is similarly effective on -1 PRF of other beta coronaviruses.?Importantly, frameshift inhibition by merafloxacin substantially impedes SARS-CoV-2 replication in Vero E6 cells, thereby providing the proof of principle of targeting -1 PRF as an effective antiviral strategy for SARS-CoV-2. |
| Alias | CI 934 |
| Molecular Weight | 379.4 |
| Formula | C19H23F2N3O3 |
| Cas No. | 91188-00-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility Information | H2O: Insoluble DMSO: < 1 mg/mL (insoluble or slightly soluble)  |
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