Search Result

Search Results for " ribosomal "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP2187	Ribosomal protein L3 peptide (202-222) amide		Others
	Ribosomal protein L3 peptide (202-222) is a peptide with the sequenceH2N-Met-Ser-His-Arg-Lys-Tyr-Glu-Ala-Pro-Arg-His-Gly-His-Leu-Gly-Phe-Leu-Pro-Arg-Lys-Arg-amide, MW=2573.		Others
T14391	Azidamfenicol		Antibacterial , Antibiotic
	Azidamfenicol inhibits ribosomal peptidyltransferase with a Ki of 22 µM. Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic.		Antibacterial , Antibiotic
T22422	S6K-18		S6 Kinase
	S6K-18, a highly selective S6K1 inhibitor, inhibits S6K1 with IC50 of 52nM.		S6 Kinase
T5428	BIX 02565		LRRK2 , S6 Kinase
	BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).		LRRK2 , S6 Kinase
T2002	PF-4708671	PF4708671	S6 Kinase , Autophagy
	PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671(PF4708671) is potent for S6K1(Ki50=20 nM, IC50=160 nM).		S6 Kinase , Autophagy
T6877	LJH685		Apoptosis , S6 Kinase
	LJH685 is an effective pan-RSK inhibitor for RSK1/2/3 (IC50: 6/5/4 nM).		Apoptosis , S6 Kinase
T4301	AD80		Raf , c-RET , Src , S6 Kinase
	AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.		Raf , c-RET , Src , S6 Kinase
T6171	BI-D1870		S6 Kinase , Autophagy
	BI-D1870 is a cell-permeable, ATP-competitive inhibitor of ribosomal S6 kinases (RSKs; IC50s: 31/24/18/15 nM for RSK1/2/3/4).		S6 Kinase , Autophagy
T6304	AT7867		Akt , PKA , S6 Kinase
	AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.		Akt , PKA , S6 Kinase
T6878	LJI308		S6 Kinase
	LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.		S6 Kinase
T14779	BRD7389		SGK , FLT , Pim , CDK , S6 Kinase , DAPK
	BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.		SGK , FLT , Pim , CDK , S6 Kinase , DAPK
T6948	Pluripotin	SC1	ERK , Raf , S6 Kinase
	Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP.		ERK , Raf , S6 Kinase
T1550	Thiamphenicol	Dextrosulphenidol,Thiophenicol	Antibacterial , Antibiotic
	Thiamphenicol (Dextrosulphenidol) is a methylsulfonyl analog of chloramphenicol. It is an antibiotic and immunosuppressive agent.		Antibacterial , Antibiotic
T6159	LY-2584702 free base		S6 Kinase , mTOR
	LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).		S6 Kinase , mTOR
T7790	Bisindolylmaleimide V		PKC , S6 Kinase
	Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.		PKC , S6 Kinase
T1746	LY-2584702 tosylate salt	LY2584702 tosylate	S6 Kinase
	LY-2584702 tosylate salt is a selective, ATP-competitive p70S6K inhibitor, used in trials studying the treatment of cancer.		S6 Kinase
T9066	Merafloxacin	CI 934	SARS-CoV
	Merafloxacin (CI 934) is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2.		SARS-CoV
T2482	AT13148		ROCK , SGK , Akt , PKA , S6 Kinase
	AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.		ROCK , SGK , Akt , PKA , S6 Kinase
T4488	GSK-25	GSK25	ROCK , S6 Kinase , mTOR
	GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).		ROCK , S6 Kinase , mTOR
T3125	Amikacin sulfate	Amikacin Sulfate Salt	ribosome , Antibacterial , Antibiotic
	Amikacin sulfate is a broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and ototoxic like the other aminoglycoside antibiotics.		ribosome , Antibacterial , Antibiotic
T8978	DD1	3,3'-Diamino-4'-methoxyflavone,HUN85111	Proteasome
	DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.		Proteasome
T6382	Amikacin disulfate	Pierami,BAY-416651 sulfate,BB-K8,Amikacin sulfate	Antibacterial , Antibiotic
	Amikacin disulfate (BAY-416651 sulfate) is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A.		Antibacterial , Antibiotic
T19913	CKI-7	CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl	ROCK , SGK , Casein Kinase , CDK , S6 Kinase
	CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.		ROCK , SGK , Casein Kinase , CDK , S6 Kinase
T6383	Amikacin hydrate	BAY416651 hydrate	Others , Antibacterial , Antibiotic
	Amikacin hydrate (BAY416651 hydrate) is an aminoglycoside antibiotic used to treat different types of bacterial infections.		Others , Antibacterial , Antibiotic
T6549	Isepamicin sulfate	Isepamicine (Isepamycin,Isepamicin Sulphate,Isepacin,sch21420) Sulphate	Antibacterial , Antibiotic
	Isepamicin sulfate (sch21420) Sulphate) , an aminoglycoside antibacterial with good activity against strains producing type I 6-acetyltransferase, inhibits bacterial protein synthesis by targeting the bacterial 30S ribos...		Antibacterial , Antibiotic
T77628	Bisindolylmaleimide III		PKC
	Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6 protein kinase 1 upon activation of these kinases.		PKC
T6448	Clindamycin hydrochloride	Sobelin HCl,Cleocin,Clindamycin HCl,Clinimycin HCl	Antibacterial , Antibiotic
	Clindamycin hydrochloride (Clinimycin HCl) inhibits protein synthesis by acting on the 50S ribosomal. It is the hydrochloride salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum antibiotic produced by ...		Antibacterial , Antibiotic
T1767	BMH-21	BMH21	DNA/RNA Synthesis
	BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.		DNA/RNA Synthesis
T1747	Tedizolid	TR 700,DA-7157,Torezolid	MAO , Antibacterial , Antibiotic
	Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of the ribosome.		MAO , Antibacterial , Antibiotic
T3052	Sancycline	Bonomycin,Norcycline,Sancyclinum,6-Demethyl-6-deoxytetracycline	Antibacterial
	Sancycline (Bonomycin) is a rare semi-synthetic tetracycline, acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.		Antibacterial
T1569	Tigecycline	GAR-936	ribosome , Antibacterial , Antibiotic , Autophagy
	Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome co...		ribosome , Antibacterial , Antibiotic , Autophagy
T12607	Quinupristin		Antibacterial , Antibiotic
	Quinupristin is a member of the macrolide-lincosamide-streptogramin class of antibiotics. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete...		Antibacterial , Antibiotic
T16491	PF-06446846 hydrochloride		Others
	PF-06446846 hydrochloride, an orally active and highly selective inhibitor, targets Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) translation by inducing ribosomal stalling at approximately codon 34, effectively ...		Others
T2211	Dihydrostreptomycin sulfate	Dihydrostreptomycin sesquisulfate	Antibacterial , Antibiotic
	Dihydrostreptomycin sulfate (Dihydrostreptomycin sesquisulfate) inhibits protein synthesis by binding to the 30S ribosomal subunit. Dihydrostreptomycin Sulfate is a semi-synthetic aminoglycoside antibiotic with bacterici...		Antibacterial , Antibiotic
T50026	Aquacycline		HSV
	Oxytetracycline (OTC) is a broad-spectrum antibiotic that acts by inhibiting protein synthesis in bacteria. Oxytetracycline prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also po...		HSV
T16567	PQR530	PQR-530	PI3K , mTOR
	PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor. PQR530 inhibited protein kinase B (PKB, pSer473) and ribosomal protein S6 (pS6, pSer235/236) phosphorylation with IC50 values of 0.07 μM. It also showing antitu...		PI3K , mTOR
T16703	Quarfloxin	CX-3543	DNA/RNA Synthesis
	Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-...		DNA/RNA Synthesis
T36675	ERK Inhibitor
	ERK inhibitor is a cell-permeable inhibitor that binds ERK2 near its docking domain (KD = 5 μM). This prevents its interaction with protein substrates without inhibiting catalytic activity. ERK inhibitor blocks ERK-speci...
T22297	Clindamycin hydrochloride monohydrate	Clindamycin alcoholate	Antibiotic
	Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentra...		Antibiotic
T25733	Lincophenicol
	Lincophenicol is an Escherichia coli ribosomal peptidyltransferase-catalyzed puromycin reaction inhibitor.
T31854	Formylmethionyl-alanyl-leucine	Fmet-ala-leu
	Formylmethionyl-alanyl-leucine is formed by E coli ribosomal protein L10 gene.
T11310	FMK-MEA		Others
	FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.		Others
T69823	MC4
	MC4 is a first-in-class inhibitor of ribosomal RNA synthesis with antimicrobial activity against Staphylococcus aureus.
T24819	Sparsomycin	U 19183,B 120121L19,B120121L19,U-19183,U19183
	Sparsomycin is an antitumor antibiotic. It also inhibits protein synthesis in the 70S and 80S ribosomal systems.
T71199	CGP7040
	CGP7040 is a rifamycin analogue, is a protein 50S ribosomal subunit inhibitor that was being developed by Novartis.
T10365	Arg-AMS		Others
	Arg-AMS is a potent arginyl tRNA synthetase inhibitor that displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes.		Others
T60385	PXYC1
	PXYC1 is a ribosomal protein S1 ( RpsA ) antagonist with K d s of 0.81 and 0.31 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. During the trans-translation process of Mycobacterium Tuberculosis (Mtb), the ribosomal pr...
T40998	S-6123
	S-6123 is a highly effective antimicrobial compound classified under the oxazolidinone series, and it acts by selectively inhibiting ribosomal protein synthesis while not affecting DNA or RNA synthesis.
T60283	PXYC2
	PXYC2 is a ribosomal protein S1 ( RpsA ) antagonist with K d s of 6.35 and 5.11 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. During the trans-translation process, the ribosomal protein S1 (RpsA) plays a key role [1]...
T71449	Capreomycin free base
	Capreomycin is a polypeptide antibiotic originally isolated from S. capreolus. It is active against M. tuberculosis (MIC = 10 µg/ml). Capreomycin binds to both the 30S and 50S ribosomal subunits, inhibiting protein synth...

Compounds

Ribosomal protein L3 peptide (202-222) amide

Target: Antibacterial, Antibiotic

Target: LRRK2, S6 Kinase

PF-4708671

T2002

Synonym: PF4708671

Target: S6 Kinase, Autophagy

LJH685

T6877

Synonym:

Target: Apoptosis, S6 Kinase

AD80

T4301

Synonym:

Target: Raf, c-RET, Src, S6 Kinase

BI-D1870

T6171

Synonym:

Target: S6 Kinase, Autophagy

AT7867

T6304

Synonym:

Target: Akt, PKA, S6 Kinase

Target: SGK, FLT, Pim, CDK, S6 Kinase, DAPK

Pluripotin

T6948

Synonym: SC1

Target: ERK, Raf, S6 Kinase

Thiamphenicol

T1550

Synonym: Dextrosulphenidol,Thiophenicol

Target: Antibacterial, Antibiotic

LY-2584702 free base

T6159

Synonym:

Target: S6 Kinase, mTOR

Bisindolylmaleimide V

T7790

Synonym:

Target: PKC, S6 Kinase

LY-2584702 tosylate salt

T1746

Synonym: LY2584702 tosylate

Target: ROCK, SGK, Akt, PKA, S6 Kinase

GSK-25

T4488

Synonym: GSK25

Target: ROCK, S6 Kinase, mTOR

Amikacin sulfate

T3125

Synonym: Amikacin Sulfate Salt

Target: ribosome, Antibacterial, Antibiotic

DD1

T8978

Synonym: 3,3'-Diamino-4'-methoxyflavone,HUN85111

Target: Proteasome

Amikacin disulfate

T6382

Synonym: Pierami,BAY-416651 sulfate,BB-K8,Amikacin sulfate

Target: Antibacterial, Antibiotic

CKI-7

T19913

Synonym: CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl

Target: ROCK, SGK, Casein Kinase, CDK, S6 Kinase

Amikacin hydrate

T6383

Synonym: BAY416651 hydrate

Target: Others, Antibacterial, Antibiotic

Isepamicin sulfate

T6549

Synonym: Isepamicine (Isepamycin,Isepamicin Sulphate,Isepacin,sch21420) Sulphate

Target: Antibacterial, Antibiotic

Bisindolylmaleimide III

T77628

Synonym:

Target: PKC

Clindamycin hydrochloride

T6448

Synonym: Sobelin HCl,Cleocin,Clindamycin HCl,Clinimycin HCl

Target: Antibacterial, Antibiotic

BMH-21

T1767

Synonym: BMH21

Target: DNA/RNA Synthesis

Tedizolid

T1747

Synonym: TR 700,DA-7157,Torezolid

Target: MAO, Antibacterial, Antibiotic

Sancycline

T3052

Synonym: Bonomycin,Norcycline,Sancyclinum,6-Demethyl-6-deoxytetracycline

Target: Antibacterial

Tigecycline

T1569

Synonym: GAR-936

Target: ribosome, Antibacterial, Antibiotic, Autophagy

Quinupristin

T12607

Synonym:

Target: Antibacterial, Antibiotic

PF-06446846 hydrochloride

T16491

Synonym:

Target: Others

Dihydrostreptomycin sulfate

T2211

Synonym: Dihydrostreptomycin sesquisulfate

Target: Antibacterial, Antibiotic

Target: DNA/RNA Synthesis

Clindamycin hydrochloride monohydrate

T22297

Synonym: Clindamycin alcoholate

Formylmethionyl-alanyl-leucine

T31854

Synonym: Fmet-ala-leu

Synonym: U 19183,B 120121L19,B120121L19,U-19183,U19183

Capreomycin free base

T71449

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T6S1302	Carnosol		Nrf2 , Endogenous Metabolite , S6 Kinase
	Carnosol is an Nrf2 activator, increasing Nrf2 levels and promoting heme oxygenase 1 (HMOX1) expression. It is a ribosomal S6 kinase (RSK2) inhibitor and can be used in gastric cancer-related research with an IC50 value ...		Nrf2 , Endogenous Metabolite , S6 Kinase
T3836	Eudesmin		MAPK , S6 Kinase
	Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 m...		MAPK , S6 Kinase
T0950	Neomycin sulfate	Framycin sulfate	Phospholipase , ribosome , Antibacterial , Antibiotic
	Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert antimicrobial activity. Neomycin sulfate is commonly used to screen prok...		Phospholipase , ribosome , Antibacterial , Antibiotic
T0895	Oxytetracycline	Terramycin	ribosome , Endogenous Metabolite , Antibacterial , Antibiotic , HSV
	Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.
T2871	Quercitrin	Sophoretin,3-rhamnosyl quercetin,Quercetin 3-rhamnoside,Xanthaurine,Meletin	Reactive Oxygen Species , S6 Kinase , Autophagy
	Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities. Quercitrin can be found in a number of food items such as garden tomato (var. ), German cam...		Reactive Oxygen Species , S6 Kinase , Autophagy
T6624	Oxytetracycline Dihydrate	Terramycin Dihydrate	Others , Endogenous Metabolite , Antibacterial , Antibiotic , HSV
	Oxytetracycline Dihydrate (Terramycin Dihydrate) is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
T0335	Sodium salicylate	Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt	Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
	Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.		Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
T21430	Oxytetracycline Hydrochloride	Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin	Antiviral , Endogenous Metabolite , Antibacterial , HSV
	Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resultin...		Antiviral , Endogenous Metabolite , Antibacterial , HSV
T1441	Capreomycin sulfate	Capastat sulfate	ribosome , Antibacterial , Antibiotic
	Capreomycin sulfate (Capastat sulfate) , a cyclic peptide antibiotic, binds to the 70S ribosomal unit leading to inhibition of protein synthesis.		ribosome , Antibacterial , Antibiotic
T16552	Pleuromutilin	Mutilin 14-glycolate,Drosophilin B	Antibacterial , Antibiotic
	Pleuromutilin (Drosophilin B) is an inhibitor of bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.		Antibacterial , Antibiotic
T16674	Pseudouridine		Endogenous Metabolite
	Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.		Endogenous Metabolite
T1313	Nitrofurantoin	Furadantine,Macrodantin,Furadonine	Antibacterial , Antibiotic
	Nitrofurantoin (Furadantine), an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoi...		Antibacterial , Antibiotic
T1304	Chlortetracycline hydrochloride	Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride	ribosome , Antibacterial , Antibiotic
	Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride (Isphamycin) is bacteriostatic and inhibits bacterial protein synthesis by b...		ribosome , Antibacterial , Antibiotic
T11233	Erythromycin thiocyanate		Antibacterial
	Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nuc...		Antibacterial
T62625	11-O-Methylpseurotin A
	11-O-Methylpseurotin A, a mixed polyketide synthase-non-ribosomal peptide synthase (PKS/NRPS) compound, selectively inhibited Hof1-deficient strains.
T16896	SL 0101-1	SL0101	S6 Kinase
	SL 0101-1 (SL0101) is a selective, efficient, reversible and ATP-competitive inhibitor of p90 ribosomal S6 kinase (RSK) that can permeate cell membranes, with an IC50 value of 89 nM for RSK.SL 0101-1 (SL0101) is also a p...		S6 Kinase

Natural Products

Carnosol

T6S1302

Synonym:

Target: Nrf2, Endogenous Metabolite, S6 Kinase

Eudesmin

T3836

Synonym:

Target: MAPK, S6 Kinase

Neomycin sulfate

T0950

Synonym: Framycin sulfate

Target: Phospholipase, ribosome, Antibacterial, Antibiotic

Oxytetracycline

T0895

Synonym: Terramycin

Target: ribosome, Endogenous Metabolite, Antibacterial, Antibiotic, HSV

Quercitrin

T2871

Synonym: Sophoretin,3-rhamnosyl quercetin,Quercetin 3-rhamnoside,Xanthaurine,Meletin

Target: Reactive Oxygen Species, S6 Kinase, Autophagy

Oxytetracycline Dihydrate

T6624

Synonym: Terramycin Dihydrate

Target: Others, Endogenous Metabolite, Antibacterial, Antibiotic, HSV

Sodium salicylate

T0335

Synonym: Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt

Target: Apoptosis, NF-κB, COX, S6 Kinase, Autophagy

Oxytetracycline Hydrochloride

T21430

Synonym: Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin

Target: Antiviral, Endogenous Metabolite, Antibacterial, HSV

Capreomycin sulfate

T1441

Synonym: Capastat sulfate

Target: ribosome, Antibacterial, Antibiotic

Pleuromutilin

T16552

Synonym: Mutilin 14-glycolate,Drosophilin B

Target: Antibacterial, Antibiotic

Pseudouridine

T16674

Synonym:

Target: Endogenous Metabolite

Nitrofurantoin

T1313

Synonym: Furadantine,Macrodantin,Furadonine

Target: Antibacterial, Antibiotic

Chlortetracycline hydrochloride

T1304

Synonym: Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride

Target: ribosome, Antibacterial, Antibiotic

Erythromycin thiocyanate

T11233

Synonym:

Target: Antibacterial

11-O-Methylpseurotin A

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00559	30S ribosomal protein S15 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. Binds to its own mR...
TMPH-00560	30S ribosomal protein S2 Protein, E. coli, Recombinant (GST)	E. coli	E. coli
	Required for ribosomal protein S1 to bind to the 30S subunit.
TMPH-00562	30S ribosomal protein S7 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, where it has be...
TMPH-00053	50S ribosomal protein L22, Anaplasma phagocytophilum, Recombinant (His & Myc)	Anaplasma phagocytophilum	E. coli
	This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with differen...
TMPH-00561	30S ribosomal protein S4 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; With S5 and S12 plays an important role in translational accuracy; ma...
TMPH-00503	60S ribosomal protein L10 Protein, Drosophila melanogaster, Recombinant (His)	Fruit fly	E. coli
	60S ribosomal protein L10 Protein, Drosophila melanogaster, Recombinant (His) is expressed in E. coli.
TMPH-00558	30S ribosomal protein S11 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
TMPJ-00947	RPS19 Protein, Human, Recombinant	Human	E. coli
	40S Ribosomal Protein S19 (RPS19) is a ribosomal protein that Belongs to the ribosomal protein S19e family. RPS19 is located in the nucleoli, and higher level expression is seen in colon carcinoma tissue than normal colo...
TMPJ-01046	RPS7 Protein, Human, Recombinant (His)	Human	E. coli
	40S ribosomal protein S7(RPS7) belongs to the S7E family of ribosomal proteins. It is phosphorylated by NEK6 during post-translational modification. RPS7 is located in the cytoplasm, binds IPO9 with high affinity. it als...
TMPH-03517	Ribosomal protein uS5 Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	With S4 and S12 plays an important role in translational accuracy.; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
TMPY-04073	MRPL44 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondria...
TMPY-05356	RPLP1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	RPLP1 Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 13.8 kDa. Accession number: A0A024R608
TMPY-04357	RSK4 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Ribosomal protein S6 kinase alpha-6, also known as Ribosomal S6 kinase 4, 9 kDa ribosomal protein S6 kinase 6,RSK-4, RSK4 and RPS6KA6, is a protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kina...
TMPY-04392	RSK3 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Ribosomal protein S6 kinase alpha-2, also known as 9 kDa ribosomal protein S6 kinase 2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, Ribosomal S6 kinase 3, RSK-3, RPS6KA2 and MAPKAPK1C, is a ...
TMPY-04540	S6K1/RPS6KB1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	PS6K, also known as RPS6KB1, is a serine/threonine-protein kinase. It belongs to the RSK (ribosomal s6 kinase) family. Members of this family function in signal transduction. PS6K is an isoform of p70 ribosomal S6 kinase...
TMPH-03461	IFM1 Protein, S. cerevisiae, Recombinant (GST)	Saccharomyces cerevisiae	E. coli
	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis o...
TMPH-00865	RPLP0 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
TMPH-02483	RPLP0 Protein, Mouse, Recombinant (His & Myc & SUMO)	Mouse	E. coli
	Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
TMPY-03751	C1orf33/MRTO4 Protein, Human, Recombinant (His)	Human	E. coli
	MRTO4 (MRT4 Homolog, Ribosome Maturation Factor) is a Protein Coding gene. MRTO4, also known as MRT4, belongs to the universal ribosomal protein uL10 family. This gene encodes a protein sharing a low level of sequence si...
TMPJ-00689	EIF1B Protein, Human, Recombinant (His)	Human	E. coli
	Eukaryotic Translation Initiation Factor 1B (EIF1B) is an element of a complex involved in recognition of the initiator codon during the scanning process. Translation is also initiated by the function of EIF1B in regulat...
TMPH-01856	Pescadillo homolog Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
TMPH-02401	RplL Protein, Legionella pneumophila, Recombinant (His & Myc)	Legionella pneumophila	E. coli
	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
TMPJ-01436	MKI67 Protein, Human, Recombinant (GST)	Human	E. coli
	MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferatio...
TMPH-01799	Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)	Human	E. coli
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPH-01798	Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)	Human	in vitro E. coli expression system
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPH-01310	EIF3G Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and ...
TMPH-00015	Abrin-d Protein, Abrus precatorius, Recombinant (His & Myc)	Abrus precatorius	E. coli
	The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA.; The B chain is a galactose-specific lectin th...
TMPH-00516	StxA2 Protein, Enterobacteria phage 933W, Recombinant (E189K, His & Myc)	Enterobacteria phage 933W	E. coli
	The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the cata...
TMPH-00014	Abrin-c Protein, Abrus precatorius, Recombinant (His & Myc)	Abrus precatorius	E. coli
	The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain...
TMPH-00013	Abrin-a Protein, Abrus precatorius, Recombinant (Yeast, His)	Abrus precatorius	Yeast
	The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain...
TMPH-00012	Abrin-a Protein, Abrus precatorius, Recombinant (E. coli, His)	Abrus precatorius	E. coli
	The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain...
TMPH-01306	EIF4A1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary str...
TMPY-02844	EBP1 Protein, Human, Recombinant (His)	Human	E. coli
	EBP1, also known as PA2G4, is an RNA-binding protein that belongs to the peptidase M24 family. It can be detected n several cell lines tested, including primary and transformed cell lines. EBP1 also present in pre-riboso...
TMPH-03707	Viscumin Protein, Viscum album, Recombinant (His)	Viscum album	Yeast
	The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. The B chain binds to cell receptors and probab...
TMPH-03289	EIF3I Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPH-03288	EIF3I Protein, Rat, Recombinant (His)	Rat	Baculovirus
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPH-00856	RPSA Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions...
TMPH-01309	EIF3F Protein, Human, Recombinant (His)	Human	E. coli
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPH-01286	EEF2 Protein, Human, Recombinant (His)	Human	E. coli
	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly form...
TMPH-01308	GSPT1 Protein, Human, Recombinant (His & Myc)	Human	Yeast
	Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ETF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which ...
TMPJ-01019	NHP2L1 Protein, Human, Recombinant (His)	Human	E. coli
	NHP2-Like Protein 1 (NHP2L1) is a member of the ribosomal protein L7Ae family. NHP2L1 proteinis limited to the nucleus, primarily focused in the dense fibrillar component of the nucleolus. NHP2L1 has been shown to intera...
TMPH-02506	ANG Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S...
TMPH-01800	Nucleolin Protein, Human, Recombinant (His)	Human	Yeast
	Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is ...
TMPJ-01396	PIN4 Protein, Human, Recombinant (His)	Human	E. coli
	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PA...
TMPH-01311	EIF3M Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPJ-00726	NEO Protein, K. pneumoniae, Recombinant	Klebsiella pneumoniae	E. coli
	Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydr...
TMPJ-01395	NIP7 Protein, Human, Recombinant (His)	Human	E. coli
	60S Ribosome Subunit Biogenesis Protein NIP7 Homolog (NIP7) belongs to the NIP7 family. NIP7 contains one PUA domain, it is essential for the process of proper 27S pre-rRNA and 60S ribosome subunit assembly. NIP7 is a mo...
TMPH-01210	DENR Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes....
TMPJ-00973	EIF1AX Protein, Human, Recombinant (His)	Human	E. coli
	Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding of the 43S complex (a 40S...
TMPJ-01410	LSM4 Protein, Human, Recombinant (His)	Human	E. coli
	U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which...
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