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Chlortetracycline hydrochloride

Catalog No. T1304Cas No. 64-72-2
Alias Isphamycin, Chlortetracycline HCl, 7-Chlorotetracycline hydrochloride

Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride (Isphamycin) is bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This tetracycline is active against a wide range of gram-positive and gram-negative organisms, spirochetes, rickettsial species, certain protozoa and Mycoplasma and Chlamydia organisms.

Chlortetracycline hydrochloride

Chlortetracycline hydrochloride

Purity: 93.87%
Catalog No. T1304Alias Isphamycin, Chlortetracycline HCl, 7-Chlorotetracycline hydrochlorideCas No. 64-72-2
Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride (Isphamycin) is bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This tetracycline is active against a wide range of gram-positive and gram-negative organisms, spirochetes, rickettsial species, certain protozoa and Mycoplasma and Chlamydia organisms.
Pack SizePriceAvailabilityQuantity
100 mg$30In Stock
200 mg$45In Stock
250 mg$50In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Purity:93.87%
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Product Introduction

Bioactivity
Description
Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride (Isphamycin) is bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This tetracycline is active against a wide range of gram-positive and gram-negative organisms, spirochetes, rickettsial species, certain protozoa and Mycoplasma and Chlamydia organisms.
In vivo
Chlortetracycline HCl exhibits inhibitory activity against a range of organisms, including Diplococcus pneumoniae (MIC: 0.098 mg/L), Streptococcus pyogenes (MIC: 0.292 mg/L), two strains of Bacillus subtilis (MICs: 0.195 mg/L and 0.15 mg/L), Streptococcus faecalis (MIC: 0.3 mg/L), and Mycobacterium ranae (0.3 mg/L). Its high affinity to a site on the 30S subunit effectively suppresses the activity of various Gram-positive and Gram-negative bacteria, including obligatory anaerobes.
AliasIsphamycin, Chlortetracycline HCl, 7-Chlorotetracycline hydrochloride
Chemical Properties
Molecular Weight515.35
FormulaC22H23ClN2O8·HCl
Cas No.64-72-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mg/mL (19.4 mM)
H2O: 10 mg/mL (19 mM)
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.9404 mL9.7021 mL19.4043 mL97.0214 mL
5 mM0.3881 mL1.9404 mL3.8809 mL19.4043 mL
10 mM0.1940 mL0.9702 mL1.9404 mL9.7021 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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