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Tigecycline

Tigecycline
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Purity:100%
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Tigecycline

Catalog No. T1569Cas No. 220620-09-7
Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic derived from tetracycline that binds to the 30S ribosomal subunit, disrupting the binding of aminoacyl-tRNA to the mRNA-ribosome complex.
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Pack SizePriceAvailabilityQuantity
5 mg$32In Stock
10 mg$52In Stock
25 mg$72In Stock
50 mg$107In Stock
100 mg$171In Stock
200 mg$261In Stock
500 mg$439In Stock
1 mL x 10 mM (in DMSO)$54In Stock
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Product Introduction

Bioactivity
Description
Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic derived from tetracycline that binds to the 30S ribosomal subunit, disrupting the binding of aminoacyl-tRNA to the mRNA-ribosome complex.
Targets&IC50
A. baumannii:1 mg/mL (MIC50), E. coli:125 ng/mL (Mean MIC), A. baumannii:2 mg/mL (MIC90)
AliasGAR-936
Chemical Properties
Molecular Weight585.65
FormulaC29H39N5O8
Cas No.220620-09-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 93 mg/mL (158.8 mM)
H2O: 92 mg/mL (157.1 mM)
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.7075 mL8.5375 mL17.0750 mL85.3752 mL
5 mM0.3415 mL1.7075 mL3.4150 mL17.0750 mL
10 mM0.1708 mL0.8538 mL1.7075 mL8.5375 mL
20 mM0.0854 mL0.4269 mL0.8538 mL4.2688 mL
50 mM0.0342 mL0.1708 mL0.3415 mL1.7075 mL
100 mM0.0171 mL0.0854 mL0.1708 mL0.8538 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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