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Mitoquinone mesylate

Catalog No. T12059L CAS 845959-50-4

Synonyms: MitoQ mesylate, MitoQ10 mesylate

Mitoquinone mesylate (MitoQ10 mesylate) is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.

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Mitoquinone mesylate, CAS 845959-50-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 31.00
5 mg	In stock	$ 72.00
10 mg	In stock	$ 113.00
25 mg	In stock	$ 228.00
50 mg	In stock	$ 372.00
100 mg	In stock	$ 549.00
500 mg	In stock	Inquiry
1 mL * 10 mM (in DMSO)	In stock	$ 109.00

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Purity: 97.12%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Mitoquinone mesylate (MitoQ10 mesylate) is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.
In vitro	Normal rat kidney (NRK) cells exposed to CS result in a ~2-fold increase in fluorescence due to mitochondrial superoxide compared with untreated cells. Mitoquinone offers significant protection against CS-induced mitochondrial superoxide generation[1].
In vivo	Mitoquinone (MitoQ) treatment nearly doubles lung MPO activity induced by Caerulein with a significant increase of serum IL-6 levels also evident at 10?mg/kg (dose 1)[2].

Synonyms	MitoQ mesylate, MitoQ10 mesylate
Molecular Weight	678.81
Formula	C38H47O7PS
CAS No.	845959-50-4

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (73.66 mM), Sonification is recommended.

H2O: < 0.1 mg/mL (insoluble)

References and Literature

1. Mitchell T, et al. The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renaltubular cells and rat kidneys. J Pharmacol Exp Ther. 2011 Mar;336(3):682-92. 2. Huang W, et al. Effects of the mitochondria-targeted antioxidant mitoquinone in murine acute pancreatitis. Mediators Inflamm. 2015;2015:901780.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Clinical Compound Library Drug Repurposing Compound Library Anti-Cancer Drug Library Immunology/Inflammation Compound Library Mitochondria-Targeted Compound Library Bioactive Compounds Library Max Bioactive Compound Library Anti-Cancer Compound Library

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Related compounds with same targets

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

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