Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM). Its IC50 values are 0.26 ± 0.03 μM (Ki for μ-calpain) and 5.33 ± 0.77 μM (Ki for m-calpain) [1]. In vitro, PD151746 targets calpain and reduces oxLDL-induced cytotoxicity [2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 59.00 | |
10 mg | In stock | $ 98.00 | |
25 mg | In stock | $ 198.00 | |
50 mg | In stock | $ 317.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 66.00 |
Description | PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM). Its IC50 values are 0.26 ± 0.03 μM (Ki for μ-calpain) and 5.33 ± 0.77 μM (Ki for m-calpain) [1]. In vitro, PD151746 targets calpain and reduces oxLDL-induced cytotoxicity [2]. |
Targets&IC50 | m-calpain:5.33 μM, μ-Calpain:260 nM |
Molecular Weight | 237.25 |
Formula | C11H8FNO2S |
CAS No. | 179461-52-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 44 mg/mL (185.5 mM)
Ethanol: 44 mg/mL (185.5 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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PD 151746 179461-52-0 Proteases/Proteasome Ubiquitination Cysteine Protease Proteasome PD-151746 PD151746 inhibitor inhibit