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Riboflavin Tetrabutyrate

Catalog No. T16747Cas No. 752-56-7

Riboflavin Tetrabutyrate, a lipophilic flavin derivative, possesses antioxidative and lipid peroxide-removing activities.

Riboflavin Tetrabutyrate

Riboflavin Tetrabutyrate

Purity: 98.34%
Catalog No. T16747Cas No. 752-56-7
Riboflavin Tetrabutyrate, a lipophilic flavin derivative, possesses antioxidative and lipid peroxide-removing activities.
Pack SizePriceAvailabilityQuantity
50 mg$33In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:98.34%
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Product Introduction

Bioactivity
Description
Riboflavin Tetrabutyrate, a lipophilic flavin derivative, possesses antioxidative and lipid peroxide-removing activities.
In vitro
Riboflavin Tetrabutyrate effectively suppresses NADPH-coupled and ascorbate-induced microsomal lipid peroxidation, also inhibiting oxygen uptake during such peroxidation. It appears to exert its antioxidative effects during or after the enzymic oxidation-reduction process, specifically after the abstraction of a hydrogen atom as a free radical from the active methylene group in polyunsaturated fatty acids[1].
In vivo
Riboflavin Tetrabutyrate may enhance lipid metabolism in patients with atherosclerosis, diabetes, and fatty liver by inhibiting lipid peroxidation, resulting in decreased serum lipid levels. Prolonged administration increases hepatic 3-ketoacyl-CoA thiolase activity, promoting beta-oxidation of fatty acids in the liver, without affecting renal 3-ketoacyl-CoA thiolase, hepatic or renal acyl-CoA synthetase, and acyl-CoA dehydrogenase activities [1][2].
Chemical Properties
Molecular Weight656.72
FormulaC33H44N4O10
Cas No.752-56-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (152.27 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5227 mL7.6136 mL15.2272 mL76.1359 mL
5 mM0.3045 mL1.5227 mL3.0454 mL15.2272 mL
10 mM0.1523 mL0.7614 mL1.5227 mL7.6136 mL
20 mM0.0761 mL0.3807 mL0.7614 mL3.8068 mL
50 mM0.0305 mL0.1523 mL0.3045 mL1.5227 mL
100 mM0.0152 mL0.0761 mL0.1523 mL0.7614 mL

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