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Riboflavin Tetrabutyrate, a lipophilic flavin derivative, possesses antioxidative and lipid peroxide-removing activities.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $33 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Riboflavin Tetrabutyrate, a lipophilic flavin derivative, possesses antioxidative and lipid peroxide-removing activities. |
In vitro | Riboflavin Tetrabutyrate effectively suppresses NADPH-coupled and ascorbate-induced microsomal lipid peroxidation, also inhibiting oxygen uptake during such peroxidation. It appears to exert its antioxidative effects during or after the enzymic oxidation-reduction process, specifically after the abstraction of a hydrogen atom as a free radical from the active methylene group in polyunsaturated fatty acids[1]. |
In vivo | Riboflavin Tetrabutyrate may enhance lipid metabolism in patients with atherosclerosis, diabetes, and fatty liver by inhibiting lipid peroxidation, resulting in decreased serum lipid levels. Prolonged administration increases hepatic 3-ketoacyl-CoA thiolase activity, promoting beta-oxidation of fatty acids in the liver, without affecting renal 3-ketoacyl-CoA thiolase, hepatic or renal acyl-CoA synthetase, and acyl-CoA dehydrogenase activities [1][2]. |
Molecular Weight | 656.72 |
Formula | C33H44N4O10 |
Cas No. | 752-56-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (152.27 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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