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Sodium 4-aminosalicylate dihydrate

Catalog No. T0020 CAS 6018-19-5

Synonyms: Sodium 4-Aminosalicylate, 4-Amino-salicylic acid sodium salt

Aminosalicylate Sodium is the sodium salt form of aminosalicylic acid, an analog of para-aminobenzoic acid (PABA) with antitubercular activity. Aminosalicylate sodium exerts its bacteriostatic activity against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing growth and reproduction of M. tuberculosis, eventually leading to cell death.

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Sodium 4-aminosalicylate dihydrate, CAS 6018-19-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Sodium 4-Aminosalicylate, 4-Amino-salicylic acid sodium salt
Molecular Weight	211.15
Formula	C7H6NNaO3·2H2O
CAS No.	6018-19-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

H2O: 198.9 mM

DMSO: 198.9 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Dinis TC, et al. Arch Biochem Biophys, 1994, 315(1), 161-169.

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Sodium 4-aminosalicylate dihydrate 6018-19-5 Microbiology/Virology NF-Κb oxidation-reduction Free radical scavengers NF-κB Antibiotic Antibacterial 4-Aminosalicylic acid sodium salt dihydrate Sodium 4-Aminosalicylate Inhibitor inhibit Bacterial 4-Amino-salicylic acid sodium salt Sodium 4 aminosalicylate dihydrate Sodium 4aminosalicylate dihydrate inhibitor

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