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Solasodine

Catalog No. T4036 CAS 126-17-0

Synonyms: Solasodin, Ubiquitin conjugating enzyme, MDM-2/p53, E1/E2/E3 Enzyme, Neuroprotective s, alkaloid, anti-inflammatory, E2 conjugating enzyme, hypotensive, antifungal, Solasodine, Inhibitor, Fungal, Ubiquitin activating enzyme, βIII-tubulin, Solancarpidine, anticancer, inhibit, E1 activating enzyme, steroidal, Apoptosis, antiatherosclerotic, doublecortin, Ubiquitin ligase, Purapuridine, E3 ligating enzyme

Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer cell line (HeLa) and human myeloid leukemia cell line (U937).

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Solasodine, CAS 126-17-0

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer cell line (HeLa) and human myeloid leukemia cell line (U937).
Targets&IC50	HeLa:12.17 ± 3.3 μM

Synonyms	Solasodin, Ubiquitin conjugating enzyme, MDM-2/p53, E1/E2/E3 Enzyme, Neuroprotective s, alkaloid, anti-inflammatory, E2 conjugating enzyme, hypotensive, antifungal, Solasodine, Inhibitor, Fungal, Ubiquitin activating enzyme, βIII-tubulin, Solancarpidine, anticancer, inhibit, E1 activating enzyme, steroidal, Apoptosis, antiatherosclerotic, doublecortin, Ubiquitin ligase, Purapuridine, E3 ligating enzyme
Molecular Weight	413.646
Formula	C27H43NO2
CAS No.	126-17-0

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 2.5 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Ma J., et al. Development and validation a liquid chromatography mass spectrometry for determiN/Ation of solasodine in rat plasma and its application to a pharmacokinetic study.J Chromatogr B AN/Alyt Technol Biomed Life Sci. 2014 Jul 15;963:24-8. 2. Sharma T., et al. Solasodine protects rat brain against ischemia/reperfusion injury through its antioxidant activity. Eur J Pharmacol. 2014 Feb 15;725:40-6.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Traditional Chinese Medicine Monomer Library Natural Product Library for HTS Anti-Tumor Natural Product Library Alkaloid Natural Product Library Drug Repurposing Compound Library Anti-Cancer Active Compound Library Ubiquitination Compound Library Apoptosis Compound Library Anti-Cancer Drug Library

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