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Sulamserod
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Catalog No. T13021Cas No. 219757-90-1
Alias RS-100302
Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related diseases.
Sulamserod
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Purity: 98.76%
Catalog No. T13021Alias RS-100302Cas No. 219757-90-1
Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $700 | 10-14 weeks | |
| 5 mg | $1,800 | 10-14 weeks |
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Purity:98.76%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related diseases. |
| In vivo | In pigs, the administration of Sulamserod at a dose of 30 mg/kg results in significant effects on electrophysiological parameters. Specifically, Sulamserod prolongs the mean effective refractory period (ERP) (14667 ms versus 11568 ms, P < 0.01) and wavelength (9.960.8 cm versus 8.360.9 cm, P < 0.01). Additionally, it reduces the dispersion of ERP (861 ms versus 1565 ms, P < 0.01) and causes a minimal slowing of conduction velocity (6765 cm/s versus 7264 cm/s, P < 0.01). Notably, Sulamserod does not induce any ventricular electrophysiological effects. Moreover, its administration leads to the termination of atrial flutter in 6 out of 8 animals and atrial fibrillation in 8 out of 9 animals. Furthermore, Sulamserod effectively prevents the reinduction of sustained tachycardia in all animals[1]. |
| Alias | RS-100302 |
| Molecular Weight | 445.96 |
| Formula | C19H28ClN3O5S |
| Cas No. | 219757-90-1 |
| Smiles | O=C(C1=CC(Cl)=C(N)C=2OCCOC21)CCC3CCN(CCNS(=O)(=O)C)CC3 |
| Relative Density. | 1.319 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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