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Suvecaltamide

Catalog No. T5632Cas No. 953778-58-0
Alias MK-8998

Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.

Suvecaltamide

Suvecaltamide

Purity: 99.29%
Catalog No. T5632Alias MK-8998Cas No. 953778-58-0
Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.
Pack SizePriceAvailabilityQuantity
5 mg$43In Stock
10 mg$73In Stock
25 mg$133In Stock
50 mg$221In Stock
100 mg$343In Stock
1 mL x 10 mM (in DMSO)$35In Stock
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Purity:99.29%
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Product Introduction

Bioactivity
Description
Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.
In vivo
MK-8998 displayed in vivo efficacy in rodent models of epilepsy and sleep.
AliasMK-8998
Chemical Properties
Molecular Weight380.4
FormulaC20H23F3N2O2
Cas No.953778-58-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (262.88 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6288 mL13.1441 mL26.2881 mL131.4406 mL
5 mM0.5258 mL2.6288 mL5.2576 mL26.2881 mL
10 mM0.2629 mL1.3144 mL2.6288 mL13.1441 mL
20 mM0.1314 mL0.6572 mL1.3144 mL6.5720 mL
50 mM0.0526 mL0.2629 mL0.5258 mL2.6288 mL
100 mM0.0263 mL0.1314 mL0.2629 mL1.3144 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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