Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 40.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 86.00 |
Description | Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM). |
Targets&IC50 | Syk:41 nM |
In vitro | In mice,Syk inhibitor II prevents FcεRI-mediated 5-HT release in RBL-2H3 cells in vitro (IC50 = 460 nM) and inhibits passive cutaneous anaphylaxis reactions (ID50 = 13.2 mg/kg, s.c.). |
Molecular Weight | 340.3 |
Formula | C14H15F3N6O |
CAS No. | 726695-51-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL
H2O: 25 mg/mL
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Syk Inhibitor II 726695-51-8 Angiogenesis GPCR/G Protein Neuroscience Tyrosine Kinase/Adaptors 5-HT Receptor Syk ATP-competitive Serotonin Receptor antigen inhibit Spleen tyrosine kinase Anti-allergic pyrimidine-carboxamide Inhibitor 5-hydroxytryptamine Receptor inhibitor