Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TCS-OX2-29 is a potent and selective OX2 receptor antagonist (IC50: 40 nM). It displays <250-fold selectivity for OX2 over OX1.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 39.00 | |
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 97.00 | |
25 mg | In stock | $ 189.00 | |
50 mg | In stock | $ 278.00 | |
100 mg | In stock | $ 497.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | TCS-OX2-29 is a potent and selective OX2 receptor antagonist (IC50: 40 nM). It displays >250-fold selectivity for OX2 over OX1. |
Targets&IC50 | OX2 receptor:40 nM |
In vitro | TCS-OX2-29 shows selectivity for ion channels, and transporters (<30% inhibition at 10 μM), which includes G-protein coupled receptors associated with food intake including galanin and neuropeptide Y[1]. TCS-OX2-29 Inhibits orexin A-induced IP3 accumulation and ERK1/2 phosphorylation in CHO cells transfected with the OX2 receptor[2]. |
Molecular Weight | 397.51 |
Formula | C23H31N3O3 |
CAS No. | 372523-75-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9 mg/mL (22.64 mM)
You can also refer to dose conversion for different animals. More
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TCS-OX2-29 372523-75-6 GPCR/G Protein Neuroscience OX Receptor HCRT Receptor TCSOX229 inhibit Inhibitor Orexin Receptor (OX Receptor) Hypocretin Receptor TCS-OX-2-29 TCS OX2 29 inhibitor