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Umbralisib R-enantiomer
🥰Excellent
Catalog No. T13140Cas No. 1532533-69-9
Alias TGR-1202 R-enantiomer, RP5264 R-enantiomer
Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against δPI3 kinase is at least 20 times lower than that of the inhibitors against other PI3K isoforms (A, β, and γ).
Umbralisib R-enantiomer
🥰Excellent
Purity: 95.61%
Catalog No. T13140Alias TGR-1202 R-enantiomer, RP5264 R-enantiomerCas No. 1532533-69-9
Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against δPI3 kinase is at least 20 times lower than that of the inhibitors against other PI3K isoforms (A, β, and γ).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 187 € | In Stock | |
| 5 mg | 455 € | In Stock | |
| 10 mg | 654 € | In Stock | |
| 25 mg | 1.168 € | In Stock | |
| 50 mg | 1.510 € | In Stock | |
| 100 mg | 1.881 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 560 € | In Stock |
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CitedSelect Batch
Purity:95.61%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against δPI3 kinase is at least 20 times lower than that of the inhibitors against other PI3K isoforms (A, β, and γ). |
| Alias | TGR-1202 R-enantiomer, RP5264 R-enantiomer |
| Molecular Weight | 571.55 |
| Formula | C31H24F3N5O3 |
| Cas No. | 1532533-69-9 |
| Smiles | CC(C)Oc1ccc(cc1F)-c1nn([C@H](C)c2oc3ccc(F)cc3c(=O)c2-c2cccc(F)c2)c2ncnc(N)c12 |
| Relative Density. | 1.43 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 9 mg/mL (15.75 mM)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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