Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 40.00 | |
5 mg | In stock | $ 89.00 | |
10 mg | In stock | $ 147.00 | |
25 mg | In stock | $ 313.00 | |
50 mg | In stock | $ 528.00 | |
100 mg | In stock | $ 769.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 98.00 |
Description | WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM) |
Targets&IC50 | DDR2:230 nM (IC50) |
In vitro | WRG-28 is a selective, extracellularly acting small molecule inhibitor of DDR2 that uniquely inhibits receptor-ligand interactions via allosteric modulation of the receptor.?By targeting DDR2, WRG-28 inhibits tumor invasion and migration, as well as tumor-supporting roles of the stroma, and inhibits metastatic breast tumor cell colonization in the lungs. |
Molecular Weight | 410.44 |
Formula | C21H18N2O5S |
CAS No. | 1913291-02-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 15 mg/mL (36.55 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
WRG-28 1913291-02-7 Tyrosine Kinase/Adaptors Discoidin Domain Receptor (DDR) WRG 28 WRG28 4T1 breast cancer cells joint destruction breast cancer Discoidin Domain Receptor BT549 CAFs HEK293 Inhibitor inhibit rheumatoid arthritis inhibitor