Shopping Cart
- Remove All
Your shopping cart is currently empty
(Z)-SU14813
Catalog No. T85345Cas No. 452105-23-6
(Z)-SU14813 is a novel tyrosine kinase inhibitor with anticardiogenic and antitumor activity that inhibits VEGFR-2, PDGFR-β, and FLT3 phosphorylation in xenograft tumors in a dose- and time-dependent manner.
(Z)-SU14813
Catalog No. T85345Cas No. 452105-23-6
(Z)-SU14813 is a novel tyrosine kinase inhibitor with anticardiogenic and antitumor activity that inhibits VEGFR-2, PDGFR-β, and FLT3 phosphorylation in xenograft tumors in a dose- and time-dependent manner.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 5 mg | $483 | In Stock | |
| 10 mg | $692 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,490 | In Stock | |
| 100 mg | $1,970 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "(Z)-SU14813"
Oxyresveratrol
trans-Oxyresveratrol, Tetrahydroxystilbene, 2,3',4,5'-tetrahydroxystilbene
T3S106829700-22-9
1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxidant activity, can reduce neuronal oxidative damage and protect hepatocytes against oxidative stress and mitochondrial dysfunction, which may be associated with activation of Nrf2.
- $31
Size
QTY
Methyl cinnamate
T5552103-26-4
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
- $44
Size
QTY
2-Ketoglutaric acid
T5980328-50-7
2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.
- $42
Size
QTY
Hexylresorcinol
Cited
4-Hexylresorcinol
T0314136-77-6
Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene utilized topically as an antiseptic for minor skin infection treatment.
- $42
Size
QTY
CitedPotassium iodide Cited
T03577681-11-0
Potassium iodide is used as the treatment of overactive thyroid and as protection of the thyroid gland from the influences of radiation from swallowed or inhaled radioactive iodine. It may be used after accidental exposure to radioactive iodine or before and after administration of medicine containing radioactive iodine.
- $56
Size
QTY
CitedBENZYLACETONE
Methyl 2-phenylethyl ketone, 4-Phenylbutan-2-one, 4-Phenyl-2-butanone
TCS17092550-26-7
Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties. Benzylacetone has a strong and reversible anti-mushroom tyrosinase effect, with IC50 values of 2.8 mM and 0.6 mM for monophenolase and biphenolase effects, respectively.
- $37
Size
QTY
Glycolic acid
T598579-14-1
Glycolic acid, an inhibitor of tyrosinase, suppresses melanin formation and is used in skincare products.
- $41
Size
QTY
Monobenzone
Benoquin
T0759103-16-2
Monobenzone (Benoquin) is a Depigmenting Agent. The mechanism of action of monobenzone is as a Melanin Synthesis Inhibitor. The physiologic effect of monobenzone is by means of Depigmenting Activity.
- $29
Size
QTY
Arbutin
β-Arbutin, Uva,p-Arbutin, p-Arbutin
T0473497-76-7
Arbutin (p-Arbutin)(β-Arbutin) is a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos and can inhibit tyrosinase and thus prevent the formation of melanin.
- $45
Size
QTY
Aloin
Barbaloin-A, Barbaloin, Barbalin, Aloin-A, Aloin(mixture of A&B)
T27421415-73-2
Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
- $45
Size
QTY
Select Batch
Purity:98.18%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | (Z)-SU14813 is a novel tyrosine kinase inhibitor with anticardiogenic and antitumor activity that inhibits VEGFR-2, PDGFR-β, and FLT3 phosphorylation in xenograft tumors in a dose- and time-dependent manner. |
| In vivo | METHODS: (Z)-SU14813 was evaluated in mouse tumor efficacy studies in C6 rat glioma (20, 40 mg/kg) and MV4 11 human AML (10, 20, 40 mg/kg) mouse models. RESULTS: (Z)-SU14813 treatment of C6 rat glioma model mice was sufficient to produce complete anti-tumor efficacy; (Z)-SU14813 treatment of MV4 11 human AML model increased mouse survival time from 23 days to 42 days. [1] |
| Molecular Weight | 442.48 |
| Formula | C23H27FN4O4 |
| Cas No. | 452105-23-6 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy (Z)-SU14813 | purchase (Z)-SU14813 | (Z)-SU14813 cost | order (Z)-SU14813 | (Z)-SU14813 chemical structure | (Z)-SU14813 in vivo | (Z)-SU14813 formula | (Z)-SU14813 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.