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AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 (IC50s: 654, 190, and 636 nM) with anti-tumor activity.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $76 | In Stock | |
5 mg | $163 | In Stock | |
10 mg | $278 | In Stock | |
25 mg | $472 | In Stock | |
50 mg | $648 | In Stock | |
100 mg | $893 | In Stock | |
1 mL x 10 mM (in DMSO) | $250 | In Stock |
Description | AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 (IC50s: 654, 190, and 636 nM) with anti-tumor activity. |
Targets&IC50 | HDAC3:654 nM, HDAC11:636 nM, HDAC6:190 nM |
Molecular Weight | 693.66 |
Formula | C33H29F6N3O5S |
Cas No. | 2361659-61-0 |
Smiles | CC(C)(C)c1ccc(CN(C(=O)CN(Cc2c(F)c(F)c(F)c(F)c2F)S(=O)(=O)c2ccc(F)cc2)c2ccc(cc2)C(=O)NO)cc1 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (144.16 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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