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Tyrphostin A25
🥰Excellent
Catalog No. T21622Cas No. 118409-58-8
Alias Tyrphostin AG 82, RG-50875, AG-82
Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.3 μM for GPR35.
Tyrphostin A25
🥰Excellent
Purity: 98.76%
Catalog No. T21622Alias Tyrphostin AG 82, RG-50875, AG-82Cas No. 118409-58-8
Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.3 μM for GPR35.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $33 | In Stock | |
| 5 mg | $52 | In Stock | |
| 10 mg | $75 | In Stock | |
| 25 mg | $123 | In Stock | |
| 50 mg | $182 | In Stock | |
| 100 mg | $269 | In Stock |
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Chalcone
β-phenylacrylophenone, phenyl styryl ketone, Cinnamophenone, benzylideneacetophenone, benzalacetophenone
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Purity:98.76%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.3 μM for GPR35. |
| Targets&IC50 | GPR35:0.94 µM, GPR35:5.3 µM |
| In vitro | In the human epidermoid carcinoma cell line A431, Tyrphostin A25 inhibited the activity of epidermal growth factor receptor kinase with an IC50 value of 3 μM.[1] |
| Alias | Tyrphostin AG 82, RG-50875, AG-82 |
| Molecular Weight | 202.17 |
| Formula | C10H6N2O3 |
| Cas No. | 118409-58-8 |
| Smiles | C(=C(C#N)C#N)C1=CC(O)=C(O)C(O)=C1 |
| Relative Density. | 1.569 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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