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Aristolochic acid B (Aristolochic Acid II) is a natural product from the Aristolochaceae taxon and is one of the main components of aristolochic acid. Aristolochic acid is a mutagen and carcinogen, and Aristolochic acid B (Aristolochic Acid II) can show a greater carcinogenic risk in vivo than Aristolochic acid I.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 68 € | In Stock | |
5 mg | 179 € | In Stock | |
10 mg | 264 € | In Stock | |
25 mg | 451 € | In Stock | |
50 mg | 647 € | In Stock | |
100 mg | 900 € | In Stock | |
1 mL x 10 mM (in DMSO) | 179 € | In Stock |
Description | Aristolochic acid B (Aristolochic Acid II) is a natural product from the Aristolochaceae taxon and is one of the main components of aristolochic acid. Aristolochic acid is a mutagen and carcinogen, and Aristolochic acid B (Aristolochic Acid II) can show a greater carcinogenic risk in vivo than Aristolochic acid I. |
In vivo | METHODS: Aristolochic acid B (Aristolochic Acid II) (5 mg/kg, intragastrically, 5 times a week for 6 weeks) was compared for DNA adduct formation and mutagenicity in the kidneys of gptδ transgenic mice. RESULTS Aristolochic acid B (Aristolochic Acid II) induced mutations at a frequency nearly two-fold higher than that induced by aristolochic acid I, showing a higher carcinogenic risk in vivo than aristolochic acid I, which may be at least partly the result of its elevated levels in the kidneys and plasma. [1] |
Alias | Aristolochic Acid II |
Molecular Weight | 311.25 |
Formula | C16H9NO6 |
Cas No. | 475-80-9 |
Smiles | OC(=O)c1cc2OCOc2c2c3ccccc3cc([N+]([O-])=O)c12 |
Relative Density. | 1.61 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 10 mg/mL (32.13 mM) Chloroform: Soluble | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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