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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,670 | 6-8 weeks | |
50 mg | $2,180 | 6-8 weeks | |
100 mg | $2,800 | 6-8 weeks |
Description | AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM). AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis: 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively). |
In vitro | The proliferation of T-cells from parachlorophenylalanine-treated mice is significantly reduced, the addition of AS19 (1 μM) completely restores T-cell proliferation after 48 hours [2]. |
In vivo | AS19 (0.5-10 mg/kg; subcutaneous injection; for 24 hours; male Wistar rats) treatment improves memory consolidation in an autoshaping Pavlovian/instrumental learning task [1]. |
Molecular Weight | 283.41 |
Formula | C18H25N3 |
Cas No. | 1000578-26-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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